摘要
1980—1987年,疟疾年平均发病率3.65±0.40‰,较解放初期下降99.25%。年平均死亡率0.11/100万。1987年发病率≥5‰的尚有14个县(市),约450多万人口,其中发病率较高的有90余万人口。疟疾流行主要发生在海南岛少数民族地区和大陆人口流动频繁的地区。海南岛的恶性疟和混合疟病例减少,恶性疟、间日疟和三日疟的比例由抗疟前的0.623:0.365:0.012变化为0.383:0.617:0。大陆地区的恶性疟只见外地输入病例,三日疟均由输血引起,目前只见间日疟流行。1983—1987年,大陆地区共出现暴发点379个,其中336个点(88.7%)由外地传染源输入引起。在临时民工住棚解剖中华按蚊、嗜人按蚊和微小按蚊,发现子孢子阳性感染。海南岛的恶性疟原虫在体内对氯喹、喹哌、氨盼喹产生抗药性,在体外对奎宁、甲氟喹亦显示轻度抗药性。
During 1980-1987,the malarial annual mean incidence in Guangdong was 3.65±0.4 per ten thousand,decreasing by 99.25% in comparison with that in the early 1950s,ans the annual mean mortality was 0.11 per million.In 1987,there were 14 counties/citied with a population of 4.5 million living in the areas where malaria annual incidence was ≥5。Malaria prevalence is serious in the minority nationalities areas of Hainan Island and in the population movement areas of the mainland of the province.The proportion of falciparum malaria and the mixed infection cases decreased markedly in Hainan Island with change of the ratio of Plasmodium falciparum,P.vivax and P.malariae from 0.632:0.365:0.012 to 0.383:0.617:0 before and after the malaria control programme fespectively.In the mainland of the province,only vivax malaria prevails now,the rlciparaum malaria cases were all imported and the quartan malaria cases induced by blood transfusion. There were 379 outbreak spots occured in the mainland of the province during 1983 -1987,336(86.7%)spots among which caused by the imported cases. The mosquito researches found Anopheles sinensis,A.anthropophagus and A.minimus with natural parasite infection. The other investigations also showed P.falciparum resistance to chloroquine,piper- aquine and amodiaquine by in rive test and certain degree resistance to quinine and mefloquine py in vitro test in Hainan Island.
出处
《中国寄生虫病防治杂志》
CSCD
1990年第3期190-193,共4页
Chinese Journal of Parasitic Disease Control
