摘要
The era of targeted cancer therapies has arrived.However,due to the complexity of biological systems,the current progress is far from enough.From biological network modeling to structural/dynamic network analysis,network systems biology provides unique insight into the potential mechanisms underlying the growth and progression of cancer cells.It has also introduced great changes into the research paradigm of cancer-associated drug discovery and drug resistance.
The era of targeted cancer therapies has arrived. However, due to the complexity of biological systems, the current progress is far from enough. From biological network modeling to structural/dynamic network analysis, network systems biology provides unique insight into the potential mechanisms underlying the growth and progression of cancer cells. It has also introduced great changes into the research paradigm of cancer-associated drug discovery and drug resistance.
基金
the National Natural Science Foundation of China (31100961,81173082,and 30873083)
关键词
系统生物学
网络分析
癌症
疗法
生物系统
模型结构
生物网络
药物发现
Targeted cancer therapy, network systems biology, network modeling, network analysis, drug discovery, drug resistance
