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外周血miRNA的诊断意义 被引量:11

Role of miRNA in peripheral blood
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摘要 microRNAs是一类广泛存在于真核细胞中的长约22个核苷酸的非编码RNA分子。外周血miRNA与生长发育及妊娠等生理现象的改变密切相关,在疾病的诊断、鉴别诊断、预后判断以及法医鉴定等方面发挥着重要作用。 MiRNAs(microRNAs) are a class of non-encoded small RNAs which are about 22 nucleotides in length, widely present in eukaryote. Recently, researchers have found that miRNAs extensively exist in mammals' peripheral blood. MiRNAs in peripheral blood are closely related to the physiological phenomenon such as growing development and pregnancy, playing an important role in the diagnosis, differential diagnosis, prognosis of human diseases and forensic identification.
出处 《分子诊断与治疗杂志》 2012年第2期131-136,共6页 Journal of Molecular Diagnostics and Therapy
基金 广东省科技计划(2011B031600315)
关键词 MIRNA 外周血 生物标志物 MiRNA Peripheral blood Biomarker
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