摘要
目的:探讨组织多普勒成像(TDI)技术评价射血分数正常的心衰患者左室长轴功能特点。方法:选取30名健康人(Ⅰ组)、EF>50%的心衰患者30名(Ⅱ组)和EF<50%的心衰患者30名(Ⅲ组)作为研究对象,采用TDI在二尖瓣环室间隔(ivs)、侧壁(l)、前壁(a)、后壁(p)、下壁(d)测量其Sm、DSm、IVCTm、TSm、Em、Am、IVRTm、TEm等指标。结果:Ⅰ组、Ⅱ组、Ⅲ组DSm、Sm逐渐减低,(P<0.05);而IVCTm、TSm逐渐升高(P<0.05);IVRTm、TEm在Ⅰ组、Ⅲ组、Ⅱ组逐渐升高(P<0.05);DSm及TEm在诊断EF>50%心衰患者心功能的指标中ROC曲线下面积最大,同样DSp及TEp在五个位点中ROC曲线下面积最大。结论:射血分数正常的心衰患者存在收缩减低;DSm及TEm是诊断EF>50%心衰患者心功能比较有效的指标;后壁是诊断的最佳位点。
Objective： To evaluate the variation of left ventricular function in the patients of heart failure with normal ejection fraction by Tissue doppler imaging.Methods： 30 healthy individuals（Group Ⅰ）,30 patients of heart failure with EF50%（Group Ⅱ） and 30 patients with EF50%（Group Ⅲ） were selected as typical samples.Tissue Doppler Imaging（TDI） was used to measure the flow velocity of 5 sites in long axis of the mitral annular systolic peak velocity（Sm）,systolic displacement（DSm）,isovolumic contraction time（IVCTm）,time to systolic velocity（TSm）,early diastolic velocity（Em）,peak velocity of trans-mitral flow by atrial contraction（Am）,isovolumic relaxation time（IVRTm）,time to diastolic velocity（TEm）.Results： The parameters Sm and DSm decreased,and IVCTm,TSm increased gradually in GroupⅠ,Ⅱ and Ⅲ（P〈0.05）.IVRTm,TEm increased gradually in Group Ⅰ,Ⅲ and Ⅱ（P〈0.05）.DSm and IVRTm had the biggest area under ROC curve respectively to evaluate left ventricular function of heart-failure patients with EF50%,DSp and IVRTp had the biggest area under ROC curve respectively in the five sites.Conclusions： The patients of heart failure with normal ejection fraction have systolic dysfunction in left ventricular long-axis.DSm and TEm are effective parameters to diagnose left ventricular function in the patients of heart failure with EF50%.DSp and TEp are the optimal sites for assessing left ventricular function in the patients of heart failure with normal ejection fraction.
出处
《现代生物医学进展》
CAS
2012年第3期479-482,448,共5页
Progress in Modern Biomedicine
关键词
组织多普勒成像
左室射血分数
射学分数正常的心衰
Tissue Doppler Imaging（TDI）
Left ventricular ejection fraction（LVEF）
Heart failure with normal ejection fraction（HFNEF）
