摘要
目的分析老年男性阻塞性睡眠呼吸暂停低通气综合征（0sAHs）患者低氧血症（氧减）与白天嗜睡的关系。方法2008年3月至2011年2月来我院就诊的147例老年男性0sAHS患者，使用Epworth嗜睡量表（ESS）自我评价嗜睡程度，并与多导睡眠呼吸监测结果结合进行分析。结果147例OSAHS患者根据ESS评分分为嗜睡组和无嗜睡组，两组氧减饱和度指数（ODD、平均血氧、最低血氧、90％氧减时间百分比（CT90）差异有统计学意义（P〈0．01）。ESS评分与ODI、平均血氧、最低血氧、CT90有相关性（r分别为0．683、-0．450、-0．583、0．507，均P〈0．01）；Logistic回归分析显示，仅ODI为ESS评分的危险因素（OR=1．11，95％CI：1．07～1．15）。而ODI与平均血氧、最低血氧、CT90呈显著相关（r值分别为-0．628、-0．763、0．689，均P〈0．01）。ODI≥23次/h时预测白天嗜睡的敏感度、特异度分别为79．2％、88．2％。结论在老年男性OSAHS患者中，氧减与白天嗜睡相关，ODI有预测白天嗜睡的价值，而平均血氧、最低血氧及CT90可能通过ODI与白天嗜睡相关。
Objective To analyze the relationship between daytime sleepiness and oxygen desaturation in the male elderly with obstructive sleep apnea /hyponea syndrome （OSAHS）. Methods 147 male elderly （aged 60 80 years） with OSAHS in our sleep laboratory from March 2008 to February 2011 were divided into daytime sleepiness and daytime non-sleepiness groups. Epworth sleeping scale （ESS） and polysomnography （PSG） were employed to detect the degree of sleepiness. Oxygen desaturation were evaluated by oxygen desaturation index （ODI）, average and minimum blood oxygen, time percentage of 900/00 oxygen desaturation （CT90）. Results There were significant differences between the two groups in body mass index （BMI） （t= --4. 157）, ODI （t= -10. 063）, average （t=5. 800） and minimum （U= 916） blood oxygen, CTgo （U= 887）and apnea/ hypopnea index （AHI） （t= -11. 361） （all P〈0. 001）. ESS scores were related with desaturation parameters of ODI, average and minimum blood oxygen and CTg0 （r= 0. 683, -0. 450, -0. 583, 0. 507, all P〈0. 001）. ODI was correlated with average and minimum blood oxygen and CT90 （r= -0. 628, -0. 763, 0. 689, all P〈0. 001）. Among parameters of oxygen desaturation, only ODI had influence on ESS scores （odds ratio = 1.11, 95% CI： 1.07- 1.15）. The sensitivity and specificity predicting daytime sleepiness at ODI ≥23 times/h were about 79.2% and 84.3%, respectively. Conclusions Daytime sleepiness is associated with oxygen desaturaion and may be predicted by ODI through which average and minimum blood oxygen and CT90 are related with daytime sleepiness in the male elderly with OSAHS.
出处
《中华老年医学杂志》
CAS
CSCD
北大核心
2012年第3期196-199,共4页
Chinese Journal of Geriatrics
基金
福建省自然基金（C0710008）
