摘要
目的建立昆明地区血清同型半胱氨酸临床参考范围。方法配制同型半胱氨酸低浓度和高浓度血清样本各一份,验证该试剂方法批内和批间不精密度;收集268例表面健康人血清检测血清同型半胱氨酸浓度,建立血清同型半胱氨酸临床参考范围。结果同型半胱氨酸低浓度水平(6.67U/L)血清样本的批内和批间不精密度分别为1.80%和2.91%;高浓度水平(16.18U/L)批内和批间不精密度分别为1.30%和1.54%。268例表面健康人中男性组和和女性组血清同型半胱氨酸浓度进行t检验分析,F=14.585,结果有统计学意义(P<0.01)。男性同型半胱氨酸均值10.53U/L,中位数9.7U/L,参考范围取单侧第95百分位值为16.8U/L;女性同型半胱氨酸均值7.84U/L,中位数7.84U/L,参考范围取单侧第95百分位值为10.6U/L。结论男性和女性表面健康人血清同型半胱氨酸浓度存在显著差异,据此本实验室按性别建立了昆明地区男性和女性血清同型半胱氨酸临床参考范围。
Objective To establish the clinical reference range of serum homocysteine in Kunming region. Methods 268 cases of serum of healthy persons were collected to test the homocysteine concentrations. Results The mean homocysteine was 10.53 U/L and median was 9.7 U/L for male, so the reference range considered 95th percentile value was 16.8 U/L. Relatively the mean was 7.84 U/L and median was 7.84 U/L and the reference range was 10.6 U/L. Conclusion We established the reference range of serum homocysteine by gender in Kunming.
出处
《临床医学工程》
2012年第3期466-467,共2页
Clinical Medicine & Engineering
