摘要
目的分析低分子肝素联合米力农对慢性肺源性心脏病急性加重期患者的治疗疗效。方法将60例慢性肺源性心脏病急性加重期的住院患者随机分为治疗组和对照组，每组各30例。对照组给予常规治疗，治疗组在常规治疗的基础上加用低分子肝素和米力农，疗程7天。观察两组患者的心衰症状、体征、心功能、肺动脉压、脑尿钠肽和D-二聚体水平的变化情况。结果治疗组有效率达90．0％，对照组有效率为66．7％，两组比较差异有统计学意义（P〈0．05）；治疗组肺动脉压、脑尿钠肽和D-二聚体水平降低程度均明显大于对照组，两组比较差异有统计学意义（P均〈0．05）。结论低分子肝素联合米力农治疗慢性肺源性心脏病急性加重期患者有效。
Objective To analyse the effect of low molecular heparin plus milrinone on acute ex- acerbation of chronic cor pulmonale. Methods 60 patients with acute exacerbation of chronic cor pulmo- nale were separated into 2 groups in random：30 patients of control group were treated with routine thera- py, while on this basis, 30 patients of treatment group were given low molecular heparin and milrinone. Course of treatment is 7 days. Symptoms and signs of heart failure, heart function, pulmonary artery pres- sure,brain natriuretic peptide（ BNP）, and D-Dimer were observed. Results The clinic effective rate of the treatment group was 90.0% ,of the control group was 66.7% , the difference was statistically signifi- cant（ P 〈 0.05 ） ;and downscale of pulmonary artery pressure（PAP） were distinctly greater than the con- trol group with the different statistical significance（ P 〈 0.05 ）. BNP and D-Dimer in the treatment group decreased obviously, the difference was statistically significant compared with the control group （P 〈 0.05 ）. Conclusion Low molecular heparin plus milrinone would be effective in treating acute exacerbation of chronic cor oulmonale.
出处
《临床内科杂志》
CAS
2012年第2期126-128,共3页
Journal of Clinical Internal Medicine
关键词
低分子肝素
米力农
慢性肺源性心脏病
肺动脉高压
Low molecular heparin Milrinone Chronic cor pulmonale Pulmonaryartery pressure
