期刊文献+

来曲唑促排卵治疗85例妊娠结局分析 被引量:6

下载PDF
导出
摘要 目的探讨来曲唑促排卵治疗妊娠后胚胎或胎儿的安全性及生长发育的影响。方法选择有排卵障碍的患者,月经第3~5天服用来曲唑片2.5~5 mg/d,共5 d,第11天阴道B超监测卵泡大小及子宫内膜情况,视卵泡大小,适当加用尿促性素,当卵泡直径≥18 cm时,注射绒促性素,48 hB超确定卵泡已排。停经后检查尿HCG或血HCG确定早孕,停经45~60 dB超确定宫内妊娠。结果应用来曲唑治疗排卵障碍的患者共402个周期,妊娠89例,其中有85例随访至妊娠结束,4例因联系电话或住址变更而失访。85例妊娠中双胎妊娠8例,单胎妊娠77例,流产15例,早产6例,新生儿死亡2例,均为双胎早产儿之一,出生73个存活婴儿,畸形2例,流产率17.65%,早产率7.06%,畸形率2.3%。双胎足月产5例,平均孕周37.71周,平均出生体重3013.50 g;单胎足月产57例,平均孕周39.28±1.07,出生体重(3451.92±459.49)g。结论来曲唑促排卵治疗妊娠后不会增加胎儿的畸形率,不会影响胚胎的生长发育。
作者 沈桂红 刘瑞
出处 《中国实用医药》 2012年第3期161-162,共2页 China Practical Medicine
  • 相关文献

参考文献6

  • 1Mitwally M,Casper R.The aromatase inhibitor,letrozole:apromising alternative for clomiphene citrate for induction of ovulation.Fertility and Sterility,2000,74(3):S35. 被引量:1
  • 2Requena A,Herrero J,Landeras J,et al.Use of letrozole in assisted reproduction a system atic review and meta-analysis.Hum Reprod Update,2008,14(6):571-582. 被引量:1
  • 3吕淑兰,曹缵孙.芳香化酶抑制剂在多囊卵巢综合征促排卵治疗中的应用[J].中国实用妇科与产科杂志,2007,23(9):684-686. 被引量:10
  • 4Biljan MM,Hemmings R,Brassard N.The outcome of 150 babies following the treatment with Letrozole or Letrozole ang gonadotropins.Fertil Steril 2005;84(Suppl.1):1-231. 被引量:1
  • 5Tulandi T,Martin T,Al-Fadhli R.et al.Congenital malformations among 911 newborns conceived after infertility treatment with letrozole or clomiphene citrate.Fertil Steril,2006,85(6):1761-1765. 被引量:1
  • 6Forman R,Gill S,Moretti M,et al.Fetal safety of letrozole and clomiphene citrate for ovulation induction.J Obstet Gynaecol Can,2007,29(8):668-671. 被引量:1

二级参考文献7

  • 1Mohamed FM,Robert F,Casper A.Use of an aromatase inhibitor for induction of ovulation in patients with an inadequate response to clomiphene citrate[J].Fertil Steril,2001,75(2):305-309. 被引量:1
  • 2Ulku B,Mustafa B,Sibel K,et al.Use of an aromatase inhibitor in patients with polycystic ovary syndrome:a prospective randomized trial[J].Fertil Steril,2006,86(5):1451-1454. 被引量:1
  • 3Gerardo B,Gerardo M,Hector F,et al.Comparison of the efficacy of the aromatase inhibitor letrozole and clomiphene citrate as adjuvants to recombinant follicle-stimulating hormone in controlled ovarian hyperstimulation:a prospective,randomized,blinded clinical trial[J].Fertil Steril,2006,86 (5):1428-1431. 被引量:1
  • 4Christopher S,William A,Davis G,et al.A prospective randomized trial comparing anastrozole and clomiphene citrate in an ovulation induction protocol using gonadotropins[J].Fertil Steril,2006,86(6):1676-1681. 被引量:1
  • 5Tulandi T,Alan H.Limiting access to letrozole-is it justified?[J].Fertil Steri1,2006,86 (5):1447-1450. 被引量:1
  • 6Tulandi T,Martin J,AI-Fadhli R,et al.Congenital malformations among 911 newborns conceived after infertility treatment with letrozole or clomiphenecitrate[J].Fertil Steril,2006,86 (6):1761-1765. 被引量:1
  • 7Mitwally MF,Biljan MM,Casper RF.Pregnancy outcome after the use of an aromatase inhibitor for ovarian stimulation[J].Am J Obstet Gynecol,2005,192:381-386. 被引量:1

共引文献9

同被引文献45

引证文献6

二级引证文献69

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部