摘要
目的探讨妊娠合并梅毒的筛查、治疗及妊娠结局,降低不良妊娠结局的发生率。方法对180例经血清学筛查并确诊为妊娠合并梅毒的临床资料进行回顾性分析,根据妊娠期是否抗梅毒治疗及治疗的早晚,将孕妇分为A组(早孕中孕开始治疗)、B组(晚孕开始治疗)、C组(未治疗),比较三组孕妇的妊娠结局。结果除去选择性引产5例,175例妊娠合并梅毒的产妇入院即确认死胎的10例,出生1周内诊断为胎传梅毒新生儿33例。A组死胎1例,B组1例,C组8例,三组比较有显著性差异(P<0.05);A组新生儿先天梅毒10例,B组10例,C组13例,三组比较有显著性差异(P<0.05)。结论妊娠合并梅毒是导致不良妊娠结局的重要因素,妊娠期及早进行规范的抗梅毒治疗能很好改善不良妊娠结局。
Objective To investigate obstetric treatment and pregnancy outcome of syphilis infection during pregnancy.Methods In a retrospective study,we evaluated 180 pregnant women（20~35 years） diagnosed with syphilis by serological assays.The 175 cases were divided into three groups apart from elective termination of pregnancy：A group for treating pregnant women during the first or second trimester of pregnancy;B group for pregnant women during late pregnancy;C group for untreated group.Results There were 103 cases screened and final diagnosed during the first or second trimester of pregnancy（A group）,41 cases screened and final diagnosed during the final of pregnancy（B group）,30 cases were not diagnosed until peripartum（C group）.Among the 175 cases,there were 1 case of fetal intrauterine death in A group,1 case in B group,8 cases in C group;there were 10 cases of congenital syphilis in A group,while 10 cases in B group and 13 cases in C group respectively.The pregnancy outcomes were observed and compared and there were significant differences in three groups（P0.05）.Conclusion Syphilis in pregnancy is a serious harmful complication to the fetus,can be well controlled through regular and earlier treatment against syphilis during pregnancy.It is also the key for improving the pregnancy outcome.
出处
《安徽医药》
CAS
2012年第2期192-193,共2页
Anhui Medical and Pharmaceutical Journal
关键词
妊娠梅毒
死胎
胎传梅毒
早期诊断
syphilis
fetal death
congenital syphilis
early diagnosis
