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近年来^(211)At放射性药物研究的新进展 被引量：1

New Progress of ^(211)At Labelled Radiopharmaceuticals Recently
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摘要 加速器制备的α核素211 At是最适宜于靶向内放射治疗的理想核素之一。本文在参考最新文献的基础上,简要介绍了211 At标记放射治疗药物近年来取得的一些可喜进展,包括211 At的制备方法、标记物实验和临床研究以及标记方法等。对211 At标记放射治疗药物研究存在的问题、现状及临床应用前景也进行了探讨。 211At, produced by cyclontron, is a promising radioisotope for tumor targeted radiotherapy due to its favorable radiobiological characteristics and cytotoxicity. The progress of radiopharmaceuticals labeled with 211 At were reviewed with 50 references in recent years, including the preparation of 211At, the experimental and clinical research of labeled compounds, labeling methods, etc. Additionally, its situation, problems and prospect were discussed.
作者 刘宁 杨远友 廖家莉 金建南
机构地区 四川大学原子核科学技术研究所辐射物理及技术教育部重点实验室
出处 《同位素》 CAS 2011年第B12期36-44,共9页 Journal of Isotopes
关键词 211At 放射性药物 进展 211 At radiopharmaceutica progress
分类号 O625.4 [理学—有机化学] R817 [理学—化学]
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参考文献50

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共引文献6

同被引文献47

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2011年 第B12期

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