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DNA双链断裂的组成与自由基清除效能的关系 被引量:7

Relationship between the Constitutes of DNA Double Strand Breaks and Scavenging Capacity
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摘要 Measured by gel electrophoresis scanning,it was shown that the double strand breaks (DSBs) of pBR322 irradiated by γ rays were constituted by two parts,αDSB and βDSB,and the relationship between α,β and scavenging capacity σwas obtained.Results showed that β/α non linearly decreased with increasing σ.Moreover,the yield of the OH free radicals reacting with DNA was analyzed. Measured by gel electrophoresis scanning,it was shown that the double strand breaks (DSBs) of pBR322 irradiated by γ rays were constituted by two parts,αDSB and βDSB,and the relationship between α,β and scavenging capacity σwas obtained.Results showed that β/α non linearly decreased with increasing σ.Moreover,the yield of the OH free radicals reacting with DNA was analyzed.
出处 《物理化学学报》 SCIE CAS CSCD 北大核心 2000年第2期184-187,共4页 Acta Physico-Chimica Sinica
基金 国家自然科学基金!(19605005)
关键词 电离辐射 甘露醇 DNA双链断裂 自由基清除效能 Irradiation, pBR322, Constitutes of DSB, Mannitol
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  • 1Milligan J R,Radiat Res,1996年,146卷,510页 被引量:1

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