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亚低温治疗急性重型颅脑损伤临床分析 被引量:5

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摘要 目的探讨早期局部亚低温治疗急性重型颅脑损伤患者的临床效果。方法将88例重型颅脑损伤患者随机分为亚低温治疗组和对照组,亚低温治疗44例,均在受伤后24h内进行亚低温治疗,直肠温度(RT)控制在32.0—35.0℃,持续3—5d,同时监测患者的生命体征、颅内压(ICP)及血糖变化;对照组44例患者应用脱水降颅压、营养神经、止血、抑制胃酸分泌、营养支持等常规治疗,直肠温度控制在36.5—37.5℃,降温但未使用冬眠疗法。结果亚低温治疗组患者伤后早期高ICP、高血糖均显著下降(均P〈0.05),无严重并发症,病死率、伤残率下降,预后显著改善。结论亚低温治疗对重型颅脑损伤患者具有脑保护作用,能提高临床疗效及生存率,改善生存质量,值得推广应用。
出处 《中国基层医药》 CAS 2012年第2期233-235,共3页 Chinese Journal of Primary Medicine and Pharmacy
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