摘要
目的探讨血浆氨基末端脑钠肽前体（NT-proBNP）对急性ST段抬高型心肌梗死患者近期预后及心功能的预测价值。方法对126例急性ST段抬高型心肌梗死患者，发病后36～48h测定NT-proBNP，记录发病1个月内心血管事件（心源性休克，心力衰竭，心源性死亡）的发生情况，发病后1个月行超声心动图检查、测定左室射血分数（LVEF）。结果发生心血管事件患者NT-proBNP水平明显高于无心血管事件患者，差异有统计学意义（P〈0．01）；发病后1个月时LVEF〈0．40患者血浆NT-proBNP水平明显高于LVEFI〉0．40患者，差异有统计学意义（P〈0．01）。结论血浆NT-proBNP水平可以预测急性ST段抬高型心肌梗死患者近期预后及心功能。
Objective To evaluate the prognostic value of N - terminal pro - brain natriuretic peptide （ NT - proBNP） in patients with acute ST elevation myocardial infarction （ASTEMI）. Methods 126 patients with ASTEMI hospitalized in our department were chosen from January 2010 to March 2011, NT- proBNP was obtained from these patients within 36 -48 hours after attack. The left ventricular ejection fraction （LVEF）and cardiovascular events（ cardiogenic shock, heart failure, cardiac death ）were recorded one months later after attack. Results The levels of NT - proBNP between patients with mainly cardiovascular events and those without cardiovascular events had a significant difference ; one months later after attack the levels of NT - proBNP in patients with LVEF 〈 0. 4 were higher than those with LVEF〉 0.40 （ P 〈 0. 01 ）. Conclusion NT - proBNP can predict the short term outcomes and heart function of STEMI patients.
出处
《浙江临床医学》
2012年第2期144-146,共3页
Zhejiang Clinical Medical Journal
关键词
急性心肌梗死心功能预后
氨基末端脑钠肽前体
Acute myocardial infarction Heart function Prognosis N -terminal pro -brain natriuetic peptide
