摘要
血栓性微血管病(thrombotic microangiopathy,TMA)是一组急性临床病理综合征。经典的血栓性微血管病主要指溶血尿毒综合征(hemolytic uremic syndrome,HUS)及血栓性血小板减少性紫癜(thrombotic thrombocytopenic purpura,TTP)。虽然血栓性微血管病在病理学上表现类似,但其发病机制复杂,诊断和治疗手段上也不尽一致。近年来随着对其发病机制的深入研究和理解,其治疗方案也有了日新月异的进步,预后大为改善。本文拟就血栓性微血管病的诊断和治疗的最新进展作一综述。
Thrombotic microangiopathy(TMA) is an acute clinical and pathological syndrome.The classic TMA mainly include hemolytic uremic syndrome and thrombotic thrombocytopenic purpura.TMA has similar pathological appearance,complex pathogenesis,and diversified diagnostic and treatment methods.Recent researches focus on the investigation and understanding of pathogenesis.The therapeutic regimens of TMA developed quickly and the prognosis of it greatly improved.The article reviews the new advances in the diagnosis and treatment of TMA in recent years.
出处
《实用医院临床杂志》
2012年第2期8-11,共4页
Practical Journal of Clinical Medicine
关键词
血栓性微血管病
诊断
治疗
溶血尿素综合征
血栓性血小板减少
Thrombotic microangiopathy
Diagnosis
Treatment
Hemolytic uremic syndrome
Thrombotic thrombocytopenia