摘要
目的:探讨降钙素原(proealcitonin,PCT)在细菌性脓毒症患儿的早期诊断及预后预测的应用价值。方法:将40例小儿全身炎症反应综合征患儿分为细菌脓毒症组(21例)和非脓毒症组(19例)。比较两组间PCT、C-反应蛋白(CRP)、白细胞(WBC)计数、中性粒细胞比例(N),随访1个月,判断预后。结果:细菌脓毒症组PCT显著高于非脓毒症组(P<0.05),但组间CRP、WBC计数、N水平差异无统计学意义(P>0.05)。严重脓毒症组PCT值显著高于非严重脓毒症组(P<0.05)。RCT浓度与预后有关,脓毒症组死亡率明显高于非脓毒症组(P<0.05)。结论:PCT可以作为判断脓毒症的早期指标,且可能反映病情程度,预测预后。
Objective： To analyze the diagnostic and prognostic value of procalcitonin for children with sepsis in early stage. Methods： Fourty patients were divided into sepsis group （19 cases） and non-sepsis group （21 cases）. The concentrations of serum PCT, C-reactive protein （CRP）, White blood cell （WBC）, Nutrophil ratio （N） were compared. Their prognosis were judged on the 30th day of the follow-up. Results： Levels of PCT in bacterial sepsis group were significantly higher than non-sepsis group （P〈0.05）, but the levels of CRP,WBC ,N were no differences （P〉0.05）. Levels of PCT in severe sep- sis group were significantly higher than non-severe sepsis group （P〈0.05）. Conclusion： Serum level of PCT can be used as a nearly indicator for judgment of sepsis for a patient with infection and reflection of severity of illness.
出处
《中国当代医药》
2011年第35期15-16,共2页
China Modern Medicine
