摘要
目的 对脂溢性角化病 (SK)及侵袭性癌进行DNA定量分析 ,以回顾性探讨两者之间的关系。方法 应用HI CI真彩色病理图像分析仪对 9例SK、16例鳞癌 (SCC)进行DNA倍体图像分析。结果 SCC多呈现C5、>C5 ,SK多呈现C3 4,但 1例SK组织病理示增生活跃 ,DNA倍体分析出现少量 ( 7.8% )的 >C5细胞 ,与SCC比较差异显著 (P <0 .0 1) ,提示部分染色体已发生了质变 ,有癌变潜在可能。结论 如临床上遇到SK有增大趋势 ,需取材做组织病理及DNA含量分析 ,对预测潜在的癌发生有重要价值。
Objective To retrospectively explore the relationships of DNA content between Sebaceous Keratosis(SK)and Squamous Cell Carcinomas(SCC).Methods DNA content of 9 cases SK and 16 cases SCC was determined by HI CI image analysis system.Results SCC DNA content showed C5、>C5,SK showed C3 4.one of 9 cases SK showed hyperplasia in HE staining and there was 7.8%>C5 cells in the DNA content.The difference was significant when compared with that of SCC(P<0.01).Conclusion It suggests when SK growing is observed in clinic,histopathologic examing and DNA content analysis are necessary and this means important value of predicting potential cutaneous carcinomas formation.
出处
《中国皮肤性病学杂志》
CAS
北大核心
2000年第2期88-89,共2页
The Chinese Journal of Dermatovenereology
