期刊文献+

下肢缺血性疾病介入治疗的临床疗效分析 被引量:9

Interventional therapy of lower limb ischemic diseases:a clinical therapeutic analysis
下载PDF
导出
摘要 目的评价下肢动脉缺血性疾病的血管造影诊断价值及介入治疗效果。方法对75例下肢动脉缺血性疾病患者行下肢动脉血管造影检查,并对检查结果进行评估,测量狭窄段血管的长度及狭窄率,将其中同意行介入治疗的30例患者(39条患肢)纳入介入治疗组,治疗使用球囊导管进行扩张,对下肢动脉严重狭窄者行自膨式支架置入术。将拒绝行介入治疗的45例患者(60条患肢)纳入保守治疗组,采用内科保守药物治疗。临床随访6~36个月,观察术中血管再通及治疗后患者下肢缺血症状改善情况。对介入治疗组和保守治疗组临床疗效进行比较。结果介入治疗组技术成功率为100%,临床有效率为90.0%,1年内发生再狭窄而导致截肢率为10.0%;保守治疗组临床有效率为62.2%,截肢率为37.8%,两组间差异有统计学意义(P<0.05)。介入治疗组3年开通率为57.7%,截肢率为23.1%。结论介入治疗下肢动脉缺血性疾病可明显改善患者临床症状,提高临床有效率,是治疗下肢动脉缺血性疾病的有效方法。 Objective To assess the value of angiography in diagnosing lower limb ischemic diseases and to discuss the therapeutic results of interventional therapy for lower limb ischemic diseases. Methods Lower limb artery DSA was performed in 75 patients with lower limb ischemic diseases. The angiographie findings were evaluated, and both the length and the stenotic rate of the diseased vessels were measured. Thirty of the total 75 patients, with 39 diseased lower limbs, agreed to receive interventional therapy (study group). Percutaneous balloon dilation was employed in the patients of study group, and self-expandable stent placement was carried out for patients with severe arterial stenosis. The remaining 45 patients who refused to accept interventional treatment (total of 60 lower limbs with symptomatic ischemia) were treated with internal conservative measures (control group). Clinical follow-up for 6 to 36 months was made. Observations on the arterial reopen and the improvement of ischemic symptoms were carefully taken. The results were compared between the two groups. Results The technical success rate and the clinical effective rate of the study group were 100% and 90.0%, respectively. The one-year amputation rate was 10.0%. The clinical effective rate and the one-year amputation rate of the control group were 62.2% and 37.8%, respectively. The difference in clinical effective rate between the two groups was statistically significant (P 〈 0.05). The 3-year patency rate and amputation rate in the study group were 57.7% and 23.1%, respectively. Conclusion Interventional treatment can markedly improve the clinical symptoms of lower limb ischemic diseases and increase the clinical effective rate. Therefore, this technique is an effective therapy for lower limb ischemic diseases.
出处 《介入放射学杂志》 CSCD 北大核心 2012年第2期111-114,共4页 Journal of Interventional Radiology
关键词 下肢动脉缺血疾病 血管造影 介入治疗 lower limb isehemie disease angiography interventional therapy
  • 相关文献

参考文献8

  • 1Eschwege E,Simon D,Balkau B.The growing burden of diabetes in the world population[J].International Diabetes Federation Bulletin,1997,42:14-19. 被引量:1
  • 2Derubertis BG,Pierce M,Ryer EJ,et al.Reduced primary patency rate in diabetic patients after percutaneous intervention results from more frequent presentation with limb-threatening ischemia[J].J Vasc Surg,2008,47:101-108. 被引量:1
  • 3肖亮,申景,黄德生,童家杰,张曦彤,徐克.糖尿病下肢动脉阻塞性病变介入治疗疗效分析[J].介入放射学杂志,2011,20(3):218-223. 被引量:13
  • 4Muradin GS,Bosch JL,Stijnen T,et al.Balloon dilation and stent implantation for treatment of femoropopliteal arterial disease:meta-analysis[J].Radiology,2001,221:137-145. 被引量:1
  • 5Perrio S,Holt PJ,Patterson BO,et al.Role of superficial femoral artery stents in the management of arterial occlusive disease:review of current evidence[J].Vascular,2010,18:82-92. 被引量:1
  • 6Lejay A,Georg Y,Bajcz C,et al.Endovascular treatment of infra-popliteal arteries in patients with critical limb ischemia[J].Acta Chir Belg,2009,109:684-693. 被引量:1
  • 7王建波,赵俊功,朱悦琦,李明华,程英升,程永德,王珏.膝下动脉经皮腔内血管成形术治疗糖尿病下肢缺血[J].介入放射学杂志,2008,17(5):318-322. 被引量:31
  • 8纪东华,王峰,Dierk Scheinert,李城,Andrej Schmidt.缺血性糖尿病下肢病变的膝下动脉成形术[J].介入放射学杂志,2008,17(5):328-331. 被引量:24

二级参考文献42

  • 1李茂全,程永德.糖尿病足介入治疗的几个问题[J].介入放射学杂志,2006,15(7):385-386. 被引量:25
  • 2方淳,李明华,程英升,程永德,张培蕾,王武.糖尿病足截肢前后血管内介入治疗临床分析[J].介入放射学杂志,2006,15(7):390-392. 被引量:22
  • 3Eschwege E, SimonD, Balkau B. The growing burden of diabetes in the world population [J]. International Diabetes Federation Bulletin, 1997, 42: 14- 19. 被引量:1
  • 4Jude EB, Oyibo SO, Chalmers N, et al. Peripheral arterial disease in diabetic and nondiabetic patients: a comparison of severity and outcome [J]. Diabetes Care, 2001, 24: 1433 - 1437. 被引量:1
  • 5DeRubertis BG, Pierce M, Ryer EJ, et al. Reduced primary pateney rate in diabetic patients after percutaneous intervention results from more frequent presentation with limb-threatening ischemia[J]. J Vasc Surg, 2008, 47(1): 101 - 108. 被引量:1
  • 6Dormandy JA, Rutherford RB, for the TASC Working Group. Management of peripheral arterial disease (PAD) [J]. J Vasc Surg,2000, 31 : S241 - 296. 被引量:1
  • 7Muluk SC, Muluk VS, Kelley ME, et al. Outcome events in patients with claudication: a 15 year study in 2777 patients[J]. J Vasc Surg, 2001, 33:251 - 258. 被引量:1
  • 8Dietzek AM, Gupta SK, Kram HB,et al. Limb loss with patent infra-inguinal bypasses [J]. Eur J Vasc Surg, 1990, 4:413 - 417. 被引量:1
  • 9Goshima KR, Mills JL Sr, Hughes JD. A new look at outcomes after infrainguinal bypass surgery: traditional reporting standards systematically underestimate the expenditure of effort required to attain limb salvage[J]. J Vase Surg, 2004, 39:330 - 335. 被引量:1
  • 10Schneider PA, Rutherford RB. Endovascular interventions in the management of chronic lower extremity ischemia [M]. // Rutherford JB, editor. Vascular Surgery 2000. 5th edition. Philadelphia, PA.. W.B. Sannders Co., 1058- 1059. 被引量:1

共引文献61

同被引文献83

引证文献9

二级引证文献14

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部