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水泡状胎块中p57、survivin、Ki-67的表达及意义 被引量：4

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摘要 目的研究p57、survivin、Ki-67在完全性水泡状胎块(complete hydatidiform mole,CHM)和部分性水泡状胎块(partial hydatidiform mole,PHM)中的表达情况,探讨其在水泡状胎块(hydatidiform mole,HM)诊断中的意义。方法应用免疫组化法检测p57、survivin、Ki-67在32例CHM、21例PHM和20例正常早孕绒毛中的表达。结果 CHM组p57的表达明显低于PHM、正常组;CHM组survivin的表达明显高于正常组;CHM组、PHM组Ki-67的表达均明显高于正常组。结论 p57可作为CHM与PHM、正常早孕绒毛鉴别的有用指标,对于p57都表达的PHM、早孕流产绒毛的鉴别,检测survivin、Ki-67的表达水平可有一定帮助。
作者 罗莹 吴荔香 廖翏 许淑霞
机构地区 福建省妇幼保健院病理科
出处 《临床与实验病理学杂志》 CAS CSCD 北大核心 2012年第2期202-204,共3页 Chinese Journal of Clinical and Experimental Pathology
关键词 水泡状胎块 P57 SURVIVIN KI-67
分类号 R714.56 [医药卫生—妇产科学]
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参考文献12

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共引文献70

同被引文献37

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二级引证文献11

临床与实验病理学杂志
2012年 第2期

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