摘要
目的探讨改良式小梁切除术联合丝裂霉素C治疗青光眼的临床疗效。方法应用改良式小梁切除术治疗42例(64眼)各型青光眼,术中一次性使用0.4mg/ml丝裂霉素C,术后随访6～12月,观察其临床疗效及其并发症。结果术后1月检查,58眼(90.6%)术后视力有不同程度的提高;术后1周测眼压,所有病例眼压均有不同程度的下降,有48眼(75.0%)眼压低于21 mmHg,术后6月测眼压,54眼(84.6%)低于21 mmHg;末次随访时,56眼(87.5%)形成弥散扁平的功能性滤过泡,8眼(12.5%)为非功能性滤过泡;总手术成功58眼(90.6%),其中完全成功54眼(84.4%),条件成功4眼(63%),失败6眼(9.4%)。术后主要并发症为:角膜水肿5眼,前房渗出4眼。讨论改良式小梁切除术联合丝裂霉素C治疗青光眼,可有效地减少青光眼术后滤过道瘢痕的形成,充分降低眼压。该方法不需要特殊设备,手术时间短、损伤小,并发症少,手术效果好,是一种安全、有效的治疗青光眼方法。
Objective To explore the clinical efficiency of modified trabeculectomy with mitomycin C（MMC） for glaucoma. Methods A total of 42 cases（64eyes） of glaucoma received the modified trabeculectomy,0.4mg/ml MMC was used in the operation.The clinical efficiency and complication was recorded.The post-operative follow-up periods ranged from 6 to 12 month.Result At 1 month, the visual acuity of 58 eyes（90.6%） increased in different levels,at 1 week,the IOP of all patients decreased in different levels and 48 eyes（75.0%） were lower than 21mmHg.At final follow-up,there were diffused and flat functioning blebs in 56 eyes（87.5%） and nonfunctioning blebs in 8 eyes（12.5%）.58 eyes（90.6%）had successful operations：54 eyes（84.4%） without medicine and 4 eyes（6.3%） with medicine.6 eyes（9.4%） failed.The postoperative complications were corneal edema（5 eyes） and anterior chamber fibrin exudalion（4 eyes）.Conclusion Modified trabeculectomy with mitomycin C for glaucoma can effectively reduce postoperative scar adhesion of the filtration passage and lower the IOP to a target level.It is safe and effective treatment for glaucoma,which had shorter time,fewer complications,a satisfying success rate and without special equipment.
出处
《实用防盲技术》
2012年第1期7-10,共4页
Journal of Practical Preventing Blind
