摘要
[目的]观察调中颗粒对寒热错杂型功能性消化不良(FD)的临床治疗效果及血浆胃肠激素水平的变化。[方法]寒热错杂型FD患者210例,随机分为2组,各105例,治疗组予调中颗粒,对照组予多潘立酮片,2组疗程均为4周。[结果]治疗组、对照组临床疗效总有效率分别为91.43%和76.19%,组间临床疗效比较,差异有统计学意义(P<0.05)。治疗组各项中医症候单项症状改善治疗前后比较差异有统计学意义(P<0.05)。治疗组血浆胃动素及促胃液素水平较前升高明显,与对照组相比差异有统计学意义(P<0.05)。2组治疗期间均未发生不良事件。[结论]调中颗粒可通过对血浆胃肠激素水平的影响缓解寒热错杂型FD患者的临床症状。
[Objective]To observe the effect of Tiaozhong granule（TG） in treating functional dyspepsia of cold and heat syndromes. [Methods]Two hundred and ten cases of functional dyspepsia of cold and heat syndromes were randomly divided into treatment group（105 cases） and control group（105 cases）. The former was administered with TG and the latter with Domperidone three times before meal each day. Both groups were under treatment for four weeks. Before and after the treatment, the efficiency was evaluated through the PAGI-SYM symptom rating scale, Chinese medical scale and the changes of motlin, gastric emptying. [Results]After the treatment, the total effective rates in the treatment group and the control group were 91.43% and 76.19% respectively（P^0.05）. Compared with the control group, the treatment group showed significant improvement in motlin and gastrin and gastric emptying（P〈0.05）. No adverse events were found in both groups. [Conclusion]TG can relieve the clinical symptoms of functional dyspepsia significantly and improve the motlin and gastric emptying by influencing the gastrointestinal hormone level.
出处
《中国中西医结合消化杂志》
CAS
2012年第2期63-66,共4页
Chinese Journal of Integrated Traditional and Western Medicine on Digestion
