摘要
目的评价稳心颗粒治疗心律失常的有效性与安全性。方法利用计算机对文献进行检索,纳入稳心颗粒治疗心律失常随机对照实验文献,数据由两名评价员分别独立提取纳入的文献,并对文献质量进行评价,使用Cochrane协作网提供的ReMan5.0软件对纳入文献进行统计分析,评价不良反应。结果 10项研究临床有效率结果显示:Chi2=11.59,df=9,P=0.24>0.05,I2=22%,具有较好的同质性,采用固定效应模型分析,其OR(fixed)=2.09,95%CI[1.45,3.01],P<0.000 01。治疗组不良反应为20例,对照组为62例。结论综合分析表明稳心颗粒是治疗心律失常的安全有效的药物。
Objective To evaluate the efficacy and safety of Wenxin Granules in the treatment of arrhythmia.Methods Literature of randomized controlled trials investing arrhythmia treatment with Wenxin Granules were searched and selected with computer.Data from the literature were collected from the literature by two reviewers independently and the qualities of the literature were also assessed.The included literature was analyzed using ReMan5.0 software provided by the Cochrane Collaboration website and adverse events were also assessed.Results 10 studies of clinical efficacy showed： Chi2=11.59,df=9,P=0.240.05,I2=22% and homogeneity was good.When the studies were analyzed using a fixed effects model,the OR（fixed） was 2.09（95%CI [1.45,3.01],P0.000 01）.The overall adverse events were 20 cases in the treatment group and 62 cases in the control group.Conclusion The comprehensive analysis shows that Wenxin Granules is a safe and effective drug for arrhythmia.
出处
《中国医药导报》
CAS
2012年第5期65-66,68,共3页
China Medical Herald
