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不同类型急性失代偿心力衰竭患者运用冻干重组人脑利钠肽治疗的临床研究 被引量:7

The clinical research of lyophilized recombinant human brain natriuretic peptide on different types of acute decompensated heart failure patients
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摘要 目的探讨冻干重组人脑利钠肽对不同类型心力衰竭患者的治疗效果。方法将本院2008年6月~2011年6月收治的190例患者按心力衰竭类型分组,各心力衰竭类型组患者随机平均分为观察组和对照组。观察组患者给予常规治疗;对照组患者在常规治疗的基础上辅以冻干重组人脑利钠肽药物治疗。分析各组患者的临床疗效。结果急性失代偿性右心力衰竭观察组患者治疗前、后的临床疗效与对照组患者比较,差异存在统计学意义(P<0.05);急性失代偿性左心力衰竭观察组患者治疗前、后的临床疗效与对照组患者比较,差异无统计学意义(P>0.05);急性失代偿性全心力衰竭观察组患者治疗前、后的临床疗效与对照组患者比较,差异存在统计学意义(P<0.05)。结论冻干重组人脑利钠肽联合常规治疗对不同程度心力衰竭患者的疗效良好,值得临床关注。 Objective To explore the treatment effect of lyophilized recombinant human brain natriuretic peptide on different types of acute decompensated heart failure patients.Methods The 190 cases of heart failure patients were randomly divided into observation group and control group in our hospital from June 2008 to June 2011 by diffrernt types of heart failure disease.The observation group were given conventional treatment;control group patients based on the routine treatment combined with new active drug treatment.The clinical efficacy between two groups patients were analyzed.Results Compared with the control group,the clinical effect of acute decompensated right heart failure patients before treatment had differences statistically significant(P 0.05);the clinical effect of acute decompensated congestive heart failure patients before treatment was not statistically significant(P 0.05);the clinical effect of acute decompensated heart failure patients before treatment had statistical significance(P 0.05).Conclusion The clinical effect of lyophilized recombinant human brain natriuretic peptide combined with conventional treatment in different levels of heart failure patients are good,it is worth the clinical attention.
作者 聂玥
出处 《中国当代医药》 2012年第3期50-51,共2页 China Modern Medicine
关键词 急性失代偿心力衰竭 冻干重组人脑利钠肽 不同类型 临床研究 Acute decompensated heart failure Lyophilized recombinant human brain natriuretic peptide Different types Clinical research
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