摘要
目的:总结33例外阴癌病例的临床资料及治疗方法,分析与外阴癌预后有关的因素。方法:回顾分析1990年1月至2011年2月我院收治的33例外阴癌的临床资料,应用SPSS软件比较分析不同的临床特点及有关预后因素。结果:33例中鳞癌20例,基底细胞癌2例,恶性黑色素瘤4例,乳房外Paget's病4例,上皮样肉瘤1例,腺样囊性癌1例,疣状癌1例。根据国际妇产科联盟(FIGO)及恶性黑色素瘤分期标准(American jointcommittee on cancer,AJCC),Ⅰ期9例(27.3%),Ⅱ期14例(42.4%),Ⅲ期9例(27.3%),Ⅳ期1例(3.0%)。无和有淋巴结受累患者的中位生存时间分别是43.0和21.5个月(P<0.05),侧位型和中线型患者的中位生存时间分别是40.0和20.5个月(P<0.05)。结论:外阴癌的治疗方式应根据病情个体化。外阴癌的预后与肿瘤部位及是否累及淋巴结等密切相关。
Objective：To summarize the clinical data,treatments and evaluate the prognostic factors of 33 vulvar cancer.Methods：Thirty three cases with vulvar cancer admitted in our hospital from Jan.1990 to Feb.2011 were retrospectively analyzed.Statistical package for social sciences（SPSS） was used to compare the different clinical characteristics and analyze the prognostic factors.Results：Twenty patients（60.6%） had squamous cell carcinoma and fifteen of them（75.0%） were well differentiated and one poorly differentiated,two had basal cell carcinoma,four had malignant melanoma,four had extramammary Paget＇s disease,one had epithelioid sarcoma,one had adenoid cystic carcinoma,one had verrucous carcinoma.According to the International Federation of Gynecologists and Obstetricians（FIGO） and American joint committee on cancer（AJCC） classification,nine cases（27.3%） were in stage Ⅰ;forteen（42.4%） in stage Ⅱ;nine（27.3%） in stage Ⅲ;one（3.0%） in stage Ⅳ.Median survival time for patients with or without lymph nodes involvement were 21.5 and 43.0 months（P0.05）.Median survival time for patients with lateral or median cancer were 40.0 and 20.5 months（P0.05）.Conclusions：The important prognostic factors for vulvar cancer were sites（lateral/median）,stage,differentiation and lymph nodes involvement.Individualized treatment should be considered.
出处
《现代妇产科进展》
CSCD
2012年第1期51-54,共4页
Progress in Obstetrics and Gynecology
关键词
外阴肿瘤
个体化治疗
预后
Vulvar neoplasms
Individualized therapy
Prognosis
