期刊文献+

阿司匹林抵抗与基因多态性的研究 被引量:2

原文传递
导出
摘要 自20世纪70年代研究发现阿司匹林可通过抑制环氧化酶(COX)而抵抗血小板的聚集后,不久阿司匹林便应用于许多血管栓塞性疾病。现在阿司匹林作为抗血小板药物已经广泛应用于血栓性疾病和心血管疾病的一级和二级预防。但是,随着研究的深入,
作者 黄洁杰 梁辉
出处 《内科理论与实践》 2012年第1期60-63,共4页 Journal of Internal Medicine Concepts & Practice
  • 相关文献

参考文献31

  • 1Gum PA,Kottke-Marchant K,Poggio ED,et al.Profile and prevalence of aspirin resistance in patients with cardiovascular disease[J].Am J Cardiol,2001,88(3):230-235. 被引量:1
  • 2Kuliczkowski W,Witkowski A,Polonski L,et al.Interindividual variability in the response to oral antiplatelet drugs:a position paper of the working group on antiplatelet drugs resistance appointed by the Section of Cardiovascular Interventions of the Polish Cardiac Society,endorsed by the working group on Thrombosis of the European Society of Cardiology[J].Eur Heart,2009,30(4):426-435. 被引量:1
  • 3O'Donnell C J,Larson MG,Feng D,et al.Genetic and environmental contributions to platelet aggregation:the Framingham heart study[J].Circulation,2001,103(25):3051-3056. 被引量:1
  • 4Faraday N,Yanek LR,Mathias R,et al.Heritability of platelet responsiveness to aspirin in activation pathways directly and indirectly related to cyclooxygenase-1[J].Circulation,2007,115(19):2490-2496. 被引量:1
  • 5Maree AO,Curtin RJ,Chubb A,et al.Cyclooxygenase-1haplotype modulates platelet response to aspirin[J].J Thromb Haemost,2005,3(10):2340-2345. 被引量:1
  • 6Gonzalez-Conejero R,Rivera J,Corral J,et al.Biological assessment of aspirin efficacy on healthy individuals:heterogeneous response or aspirin failure?[J].Stroke,2005,36(2):276-280. 被引量:1
  • 7Hillarp A,Palmqvist B,Lethagen S,et al.Mutations within the cyclooxygenase-1 gene in aspirin non-responders with recurrence of stroke[J].Thromb Res,2003,112(5-6):275-283. 被引量:1
  • 8Takahashi S,Ushida M,Komine R,et al.Platelet responsiveness to in vitro aspirin is independent of COX-1and COX-2 protein levels and polymorphisms[J].Thromb Res,2008,121(4):509-517. 被引量:1
  • 9Li Q,Chen BL,Ozdemir V,et al.Frequency of genetic polymorphisms of COX1,GPⅢa and P2Y1 in a Chinese population and association with attenuated response to aspirin[J].Pharmacogenomics,2007,8(6):577-586. 被引量:1
  • 10杨蓉,焦洁茹,蔡伟,王学锋,丁秋兰,吴方.阿司匹林抵抗与基因多态性的相关性研究[J].诊断学理论与实践,2009,8(6):623-626. 被引量:13

二级参考文献40

  • 1周畅,张晨,陈红兵,金丽英,杨学伟,郭云良.血小板膜糖蛋白Ia C_(807)T基因多态性与脑血管疾病易感性的关系研究[J].中国全科医学,2005,8(8):612-614. 被引量:1
  • 2Faraday N, Yanek LR, Mathias R, et al. Heritability of platelet responsiveness to aspirin in activation pathways directly and indirectly related to cyclooxygenase-1 [J]. Circulation, 2007, 115(19):2490-2496. 被引量:1
  • 3Maree AO, Curtin RJ, Chubb A, et al. Cyclooxygenase-1 haplotype modulates platelet response to aspirin [J]. J Thromb Haemost, 2005, 3(10):2340-2345. 被引量:1
  • 4Gonzalez-Conejero R, Rivera J, Corral J, et al. Biological assessment of aspirin efficacy on healthy individuals: heterogeneous response or aspirin failure? [J]. Stroke, 2005, 36(2):276-280. 被引量:1
  • 5Hillarp A, Palmqvist B, Lethagen S, et al. Mutations within the cyclooxygenase-1 gene in aspirin non- responders with recurrence of stroke [J]. Thromb Res, 2003, 112(5-6):275-283. 被引量:1
  • 6Takahashi S, Ushida M, Komine R, et al. Platelet responsiveness to in vitro aspirin is independent of COX- 1 and COX-2 protein levels and polymorphisms [J]. Thromb Res, 2008, 121(4): 509-517. 被引量:1
  • 7Li Q, Chen BL, Ozdemir V, et al. Frequency of genetic polymorphisms of COX1, GPIIIa and P2Y1 in a Chinese population and association with attenuated response to aspirin[J]. Pharmacogenomics, 2007, 8(6):577-586. 被引量:1
  • 8Cambria-Kiely JA, Gandhi PJ. Aspirin resistance and genetic polymorphisms[J]. J Thromb Thrombolysis, 2002, 14(1):51-58. 被引量:1
  • 9Dropinski J, Musial J, Sanak M, et al. Antithrombotic effects of aspirin based on PLA1/A2 glycoprotein IIIa polymorphism in patients with coronary artery disease[J]. Thromb Res, 2007, 119(3):301-303. 被引量:1
  • 10Goodman T. Ferro A, Sharma P, et al. Pharmacogenetics of aspirin resistance: a comprehensive systematic review [J]. Br J Clin Pharmacol, 2008,66(2): 222-232. 被引量:1

共引文献28

同被引文献6

引证文献2

二级引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部