摘要
目的了解重症监护病房(ICU)呼吸道感染鲍氏不动杆菌耐药性变迁,为临床控制多药耐药菌感染提供依据。方法对2008-2010年医院痰标本分离的908株鲍氏不动杆菌进行药敏测定,并针对多药耐药性进行干预。结果 2009年鲍氏不动杆菌的耐药性比2008年增加,氨曲南、头孢曲松、头孢噻肟、哌拉西林耐药率>90.0%,2010年通过干预措施后鲍氏不动杆菌的耐药性比2009年有延缓趋势,氨曲南、头孢曲松、哌拉西林耐药率<75.0%。结论鲍氏不动杆菌呈多药耐药性,应重视医护人员手卫生,加强口腔护理和消毒隔离,合理使用抗菌药物。
OBJECTIVE To study the change of drug resistance of Acinetobacter baumannii in the intensive care unit of our hospital,and to provide the reference for controlling the infection of drug resistant bacteria. METHODS Antibiotics susceptibility test of 908 strains of A.baumannii was performed from 2008 to 2010,and multidrug resistance was intervened. RESULTS Drug resistance of A.baumannii was increased in 2009 compared to 2008.The resistance rates to aztreonam,ceftriaxone,cefotaxime,piperacillin were 90.0%.Through intervention measures,drug resistance was reduced in 2010,the resistance rates to aztreonam,ceftriaxone,piperacillin declined to 75.0%. CONCLUSION A.baumannii are multiple antimicrobial-resistant bacteria.To control the infection caused by A.baumannii in ICU,medical staff hand hygiene,oral care,disinfection,isolation,rational use of antimicrobial agents should be highlighted.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2012年第3期617-619,共3页
Chinese Journal of Nosocomiology
关键词
鲍氏不动杆菌
耐药变迁
干预
Acinetobacter baumannii
Drug resistance changes
Intervention
