摘要
随着人口的老龄化及人类寿命的延长,骨关节炎也越来越多见。随着对骨关节炎关节软骨退变发病机制认识的不断深化,研究工作者们从骨关节炎危险因素到病理学改变,从分子生物学改变到免疫学改变,多方面、多角度地研究骨关节炎的发病机制。阐明骨关节炎软骨退变的发病机制,将有利于提高对骨关节炎的认识,也是指导骨关节炎实验研究及临床治疗的理论依据。
With the proportion of aged population edging up and the average life-span increasing,osteoarthritis are increasingly prevalent.Along with the deepening recognition of the pathogenesis of articular cartilage degeneration in osteoarthritis,researchers study from the risk factors of osteoarthritis to the change of pathology,also from the change of molecular biology to the change of immunology,various respects and angles study the mechanism of osteoarthritis.To clarify these factors mechanism in the articular cartilage degeneration will profit to raise recognition of the osteoarthritis,but also is the theoretical basis to guide the experiment study and clinical treatment of osteoarthritis.
出处
《医学综述》
2012年第3期404-406,共3页
Medical Recapitulate
关键词
骨关节炎
关节软骨
软骨下骨
退变
Osteoarthritis
Articular cartilage
Subchondral bone
Degeneration
