摘要
继发性嗜血性淋巴组织细胞增生症(SHLH)是一组单核/巨噬细胞系统异常活化导致的致死性疾病,多继发于感染、恶性肿瘤、风湿性疾病等。SHLH预后与原发病有很大的关系。在引入HLH-94及随后的HLH-04方案后,SHLH预后有了明显的改善。SHLH的治疗取决于原发病的性质和病情,严重者采用自体骨髓移植有望治愈。
Secondary hemophagocytic lymphohsitiocytosis（SHLH）is a series of fatal diseases resulted from abnormally activated monocyte/macrophage system,which is often secondary to infection,malignancy tumor,and rheumatic disease.SHLH prognosis is greatly related with the primary disease.After the introduction of HLH-94 and HLH-04 solution,prognosis of SHLH has been improved significantly,while the treatment for SHLH depends on the nature and condition of the primary disease,auto bone marrow transplantation is a hope for the cure of severe cases.
出处
《医学综述》
2012年第3期392-394,共3页
Medical Recapitulate
关键词
嗜血性淋巴细胞增生症
继发性
治疗
Hemophagocytic lymphohistiocytosis
Secondary
Treatment
