期刊文献+

合成萘普西诺的工艺改进

Process Improvement on the Synthesis of Naproxcinod
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摘要 以(S)-萘普生为原料,经酯化、硝酸酯化反应合成了萘普西诺,总收率39.9%,纯度99.1%,其结构经1H NMR,IR和MS确证。 Naproxcinod was synthesized from(S)-naproxen by esterification,then nitration in overall yield of 39.9% with purity 99.1%.The structure was confirmed by 1H NMR,IR and MS.
出处 《合成化学》 CAS CSCD 北大核心 2012年第1期128-129,共2页 Chinese Journal of Synthetic Chemistry
关键词 萘普西诺 (S)-萘普生 药物合成 工艺改进 naproxcinod (S)-naproxen drug synthesis process improvement
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参考文献9

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二级参考文献5

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