摘要
目的研究糖尿病患者胰腺CT形态学改变及其与胰岛功能的相关性。方法分析78例糖尿病患者和130例正常对照者的胰腺CT及临床资料，对两组胰腺头、体、尾3个部位作前后径测量，并对其胰腺形态与胰岛功能进行相关分析。结果正常对照组胰腺前后径的峰值在41～50岁之间，50岁以后胰腺逐步萎缩。胰腺前后径的缩小以头及体部为主。糖尿病组患者胰头、体、尾三部位前后径测量较正常对照组均显著萎缩（P〈0．01）。糖尿病患者每单位体表面积的胰腺体积与空腹C肽之间进行趋势分析，无明显相关（P〉0．05）。结论本研究揭示了正常个体胰腺前后径的峰值在41～50岁之间，50岁以后胰腺逐步萎缩。糖尿病患者的胰腺可有不同程度的萎缩，但其胰腺体积与胰岛功能之间无明显相关性。
Objective To investigate the morphological changes of the pancreas on CT and the relationship between the morphology and islet function in diabetic patients. Methods CT examination and clinical datas of 78 diabetic patients and 130 control subjects were analyzed. The A-P diameters of the head, body and tail of the pancreas. The relationship between the mophology and islet function was analyzed. Results The peak of A-P diameters in control group was between 41 and 50 years old. All parts of the pancreas tended to be smaller after 50 year old. The degree of reduction in the diameter of various portion of pancreas were varied. The atrophy of the head, body and tail of the pancreas was more obvious in diabetic group than in control group （ P 〈 O. O1 ）. There was no relationship between the pancreas volume per body surface area unit and fasting plasma C-peptide （P 〉 0. 05 ）. Conclusions The peak of A-P diameters in control group is between 41 and 50 years old. The endocrine pancreas islets has atrophic effect. The diabetic pancreas might have various degree of atrophy. But there is no significant relationship between the morphology and islet function in diabetic patients.
出处
《中国实用医刊》
2012年第4期18-21,共4页
Chinese Journal of Practical Medicine
