摘要
目的:探讨颈动脉粥样斑块与缺血性脑卒中、颅内动脉瘤的关系。方法:分别对104例缺血性脑卒中患者和126例健康体检者进行回顾性分析。所有病例均行头颈部64排CT血管造影,分析并记录颈动脉粥样斑块的类型、狭窄程度及颅内动脉瘤。结果:(1)梗塞侧颈动脉的中度狭窄率、重度狭窄或闭塞率明显高于正常侧,差异具有统计学意义(P<0.001)。梗塞侧颈动脉的易损斑块率明显高于正常侧,差异具有统计学意义(P<0.001)。(2)颈动脉粥样硬化组颅内动脉瘤发生率高于无硬化组,差异具有统计学意义(P=0.037)。结论:(1)颈动脉狭窄、易损斑块是缺血性脑卒中的重要危险因素。(2)颈动脉粥样硬化对颅内动脉瘤的发生、发展起着重要作用,同时增加了患者的危险性。(3)64排CT能清晰显示颈动脉狭窄及粥样斑块的形态和成分,可作为临床首选的检查方法。
Objective To investigate the relationships between carotid atheresclerotic plaque and cerebral ischemic stroke, intracranial aneurysm. Methods Two hundred and thirty patients were divided into two groups： cerebral ischemic stroke group （n = 104） and control group （n = 126）. All patients received 64-slice CTA detection. The type and degree of artherosclerotic plaques and intracranial aneurysm were recorded. Results The moderate, severe, and occlusion rates of carotid artery stenosis and the percentage of vulnerable plaque in infarct side were significantly higher than those in healthy side （P = 0.001 ,P 〈 0.001 ,P 〈 0.001）. The incidence of intracranial aneurysm in patients with carotid atherosclerosis was significantly higher than those without carotid atherosclerosis （P = 0.037）. Conclusions The degree of carotid artery stenosis and vulnerable plaque are risk factors for cerebral ischemia, and carotid artherosclerosis plays an important roles in the development and progression of intracranial aneurysm. 64-slice CT can clear display morphology and component of plaque, and could be used as the preferred clinical examination.
出处
《实用医学杂志》
CAS
北大核心
2012年第3期402-405,共4页
The Journal of Practical Medicine
关键词
卒中
CT血管造影
易损斑块
颅内动脉瘤
Stroke
Computed tomography angiography
Vulnerable plaque
Intracranial aneurysm
