期刊文献+

猪繁殖与呼吸综合征病毒基因表达调控序列的初步解析

GENE EXPRESSION AND REGULATORY ELEMENTS OF PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS
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摘要 猪繁殖与呼吸综合征(porcine reproductive and respiratory syndrome,PRRS)是世界养猪业的一个巨大的威胁。近年来,此病给各国养猪业造成了巨大的经济损失。本文立足于反向遗传操作技术,介绍了调控PRRS病毒粒子的感染性、基因组RNA复制、亚基因组mRNA转录以及翻译等重要过程的顺式调控元件的一级序列和高级结构的最新研究进展。 Porcine reproductive and respiratory syndrome virus (PRRSV) remains a tremendous threat to swine industry worldwide, causing significant economic losses in the past years. This review summarizes the application of reverse genetic system in PRRSV biology and recent research progress in the primary sequences and high-ordered structures of PRRSV cis-acting element in regulating virus infection, genomic replication, sg mRNA transcription and gene expression,
出处 《中国动物传染病学报》 CAS 2011年第6期65-70,共6页 Chinese Journal of Animal Infectious Diseases
基金 国家自然科学基金重点项目(30530580)
关键词 非翻译区 茎环结构 假结 untranslated region (UTR) stem-loop structure (SLS) pseudoknot
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参考文献15

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