摘要
目的探讨显微睾丸取精（TESE）结果对非梗阻性无精子症患者勃起功能的影响。方法我院门诊筛选出68例拟行试管婴儿需TESE的非梗阻性无精子症患者，平均年龄为33．6岁（23～52岁）。根据取精成功与否分成两组：A组为取精成功者，B组为取精失败者。手术前后，分别采用国际勃起功能指数调查问卷（IIEF-5问卷）评价两组受试者的勃起功能状况，同时采用焦虑白评量表（SAS问卷）及抑郁自评量表（SDS问卷）调查受试者精神状态，并检测血清中睾酮（T）、黄体生成素（LH）及卵泡刺激素（FSH）的含量，比较手术前后两组受试者各项指标是否存在差异。结果68例受试者中，27例（39．7％）取精成功。显微睾丸取精后，IIEF．5问卷评分、SAS及SDS问卷评分与术前相比，A组评分无显著性差异，B组IIEF．5评分显著下降，SAS及SDS问卷评分显著增高（P〈0．05）：两组患者术后血清T水平均显著降低，LH及FSH水平均显著升高（P〈0．05）。结论TESE术后，B组勃起功能显著下降，并存在明显的焦虑抑郁状态，A组勃起功能及焦虑抑郁状态无明显改变，两组受试者血清T水平较术前均显著降低。精神障碍可能是导致TESE失败患者勃起功能障碍的主要原因。
Objective To evaluate the effect ofmicrosurgical testicular sperm extraction （TESE） on the erectile function in patients with nonobstructive azoospermia. Methods Microsurgical testicular sperm extraction was applied to 68 infertile men diagnosed with nonobstructive azoospemia at a mean age of 33.6 years. Furthermore, the patients were divided into 2 groups. The result of Group A was successful and that of Group B failed. Before and 3 months after the surgery, the patients were evaluated based on the International Index of Erectile Function-5 （IIEF-5）, Self-Rating Anxiety Scale （SAS）, Self-Rating Depression Scale （SDS） and hormone level. Results Out of 68 cases, 27 （39.7%） experienced positive results for the TESE before and 3 months after the surgery, About IIEF-5, SAS and SDS score, there was no significant difference in Group A, while there was significant decrease in IIEF-5 score and significant increase in SAS and SDS score in Group B （P〈0.05）. The mean total testosterone level significantly decreased and the mean luteinizing hormone and follicle-stimulating hormone significantly increased in the two groups after the surgery （P〈0.05）. Conclusion After the surgery, there is significant decrease in the erectile function and there is significant increase in anxiety and depression, while there is no significant difference in patients of the successful group. Compared with the preoperative condition, in groups both the serum total testosterone level was significantly reduced. It is thought that mental disorders may play an important role in erectile dysfunction in patients with unsuccessful microsurgical testicular sperm extraction.
出处
《中国男科学杂志》
CAS
CSCD
2011年第12期26-29,共4页
Chinese Journal of Andrology
关键词
取精术
勃起功能障碍
不育
男性
sperm retrieval
erectile dysfunction
infertility, male
