摘要
目的:探讨肝内胆管细胞癌预后的影响因素,为临床治疗提供依据。方法:分析2000.6～2007.1月收治的53例肝内胆管细胞癌患者的临床资料。结果:53例患者中根治性手术组1、3、5年生存率为70.1%、40.3%、20.1%;R1手术组1、3年生存率为38.1%和0%,开腹探查组1、3年生存率为25.1%和0%。单因素分析显示,丙氨酸氨基转移酶、淋巴结转移、手术切除与预后相关(P<0.01);Cox比例风险模型多因素分析显示,根治性切除(P<0.01)、淋巴结转移(P<0.01)是影响预后的独立因素。结论:根治性手术切除可使患者具有较高的术后生存率。
Objective：To explore factors related to the prognosis of patients with intrahepatic cholangiocarcinoma.Methods：Clinical data of 53 cases of intrahepatic cholangiocarcinoma was retrospectively analyzed.Results：The 1,3,5-year survival rate of patients undergoing radical resection was 70.1%,40.3%,20.1%.While for those underwent R1 resection,the 1,3-year survival rate was 38.1%,0%.Patients underwent exploratory surgery had 1,3-year survival rate of 25.1% and 0%.Univariate analysis revealed that Alanine aminotransferaese（ALT） level,lymph node involvement and surgery were factors significantly affecting the survival rate（P0.01）.Cox proportional hazards multivariate analysis showed radical resection（P0.01）,lymph node metastasis（P0.01） were independent factors affecting prognosis.Conclusion：Radical surgery patients can prolong patients＇ survival rate.
出处
《海南医学院学报》
CAS
2012年第1期52-54,共3页
Journal of Hainan Medical University
基金
海南医学院科研基金资助学报项目(0020120014)~~
关键词
肝内胆管细胞癌
手术
预后
生存率
Iintrahepatic cholangiocarcinoma
Surgery
Prognosis
Survival rate
