摘要
目的探讨联合检测多种肿瘤标志物对肺癌的临床诊断价值。方法选择我院2007年2月～2010年12月入院治疗的35例肺癌患者,另选择35例良性肺疾病患者作为对照组,分别检测两组患者的癌胚抗原、血清糖类抗原CA19-9、神经元特异性烯醇化酶及细胞角蛋白19片段等4项肿瘤标志物。结果两组患者单种肿瘤标志物阳性率比较差异无统计学意义(P>0.05),4项联合标记物指标阳性率比较差异有统计学意义(P<0.05);各项肿瘤标记物联合检测对肺癌临床诊断的敏感度为50.04%,特异度为93.42%,准确度为72.94%。结论联合检测4项肿瘤标志物对肺癌的诊断具有重要意义,优于其他单项检测,为肺癌诊断及鉴别诊断提供了更有力的临床依据。
Objective To discuss clinical diagnostic value of combined detection multiple tumor marker contents in the lung cancer. Methods Selected 35 cases of lung cancer and another 35 cases of benign lung diseases as a control group admitted in our hospital from February 2007 to December 2010.Detected the levels of CEA,serum CA19-9,NSE and CYFRA21-1. Results The levels of single tumor markers in lung cancer group showed no significant difference from benign lung diseases group （P〉0.05）,various levels of tumor markers for diagnosis of lung cancer had a sensitivity of 50.04%, specificity of 93.42%,accuracy of 72.94%. Conclusion Combined detection of 4 tumor markers for the diagnosis of lung cancer is great significance, is better than individual testing, provides more powerful evidence for diagnosis and differential diagnosis of lung cancer.
出处
《中国现代医生》
2012年第2期66-67,共2页
China Modern Doctor
关键词
肺癌
肿瘤标志物
糖类抗原
癌胚抗原
Lung cancer
Tumor marker
Carbohydrate antigen
Carcinoembryonic antigen
