摘要
目的探讨接受辅助生殖技术(ART)助孕后发生异位妊娠(EP)的相关因素。方法对我中心2006年11月至2010年6月接受体外受精-胚胎移植(IVF-ET)、卵胞浆内单精子注射-胚胎移植(ICSI-ET)、冻融胚胎移植(FET)治疗后发生EP的病例进行回顾性分析。结果 4,219个周期获妊娠1,773例(42.02%),EP 52例,发生率2.93%(52/1,773),其中单纯输卵管妊娠占88.46%(46/52),宫内外同时妊娠3例,发生率5.77%(3/52),宫颈妊娠、卵巢妊娠、宫角妊娠各1例,发生率各占1.92%(1/52);3种ART方式发生率比较,IVF-ET显著高于ICSI-ET和FET(P<0.05),ICSI-ET和FET无统计学差异;异位妊娠史、盆腔手术史、输卵管炎和子宫内膜异位症是发生EP的重要危险因素,胚胎移植数与EP发生无显著相关性。结论输卵管因素是ART后发生EP的主要因素。
Objective. To investigate the relevant factors technology （ART）. of the ectopic pregnancy （EP） after assisted reproductive Methods. The patients who had EP after in vitro fertilization-embryo transfer （IVF-ET , intracytoplasmic sperm injection-embryo transfer （ICSI-ET）, or frozen embryo transfer （FET） in this Center from November 2006 to June 2010 were retrospectively analyzed. Results： Among 4,219 treatment cycles, there were 1,773 pregnancies achieved （42. 02%）. The incidence of EP was 2. 93 % （52/1, 773）. Among them, there were 46 cases of tubal pregnancy （88.46%）, 3 cases of both intrauterine and tubal pregnancy （5. 77%）, and I case each for cervical, cornual and ovarian pregnancy. In the three ways of ART, the incidence of EP of IVF-ET was significantly higher than that of ICSI- ET or FET （P〈0.05）. There was no significant difference between ICSI-ET and FET. The risk factors for EP were history of ectopic pregnancy, pelvic surgery, endometriosis, and salpingitis. The number of embryos transferred was not significantly correlated with EP. Conclusions. Tubal factor was the major risk factor for ectopic pregnancy after ART treatment.
出处
《生殖医学杂志》
CAS
2011年第6期465-469,共5页
Journal of Reproductive Medicine
关键词
辅助生殖技术
异位妊娠
相关因素
Assisted reproductive techniques
Ectopic pregnancy
Related factors
