摘要
患者因输血而感染HCV,在应用泼尼松治疗肾病同时,HCV复制激活,引起肾功能损害,肾病理检查提示膜型肾小球肾炎、系膜增生性病变伴肾小球硬化、肾小管-间质慢性病变及血管壁内膜增厚、肾组织有HCV抗体;给予IFNα300万U隔日1次,皮下注射,联合利巴韦林0.3 mg,3次/d,疗程12个月,尿蛋白降低,肾功能改善,浮肿消退。
One patient was infected with HCV by blood transfusion. The replication of HCV RNA was activated by prednisone accompa- nied with wores renal function. The membranous glomeruloncphritis, mesangial proliferative glomcrulonephritis associated with glomeruloscle- rosis, tubulointestina] chronic lesions, and thickening of the vessel wall intima were observed. The patient was given with IFN combined with ribavirin.
出处
《胃肠病学和肝病学杂志》
CAS
2011年第12期1152-1153,共2页
Chinese Journal of Gastroenterology and Hepatology