摘要
盐敏感性高血压是基因机制、离子转运机制、内皮功能障碍机制、肾脏机制、交感神经系统和中枢神经系统机制、肾素-血管紧张素-醛固酮机制、内分泌机制、胰岛素抵抗机制等等共同作用的结果。除了限盐治疗以外,其他针对盐敏感性高血压的降压措施包括补充钾离子和钙离子,降压药治疗,免疫疗法,基因疗法等等。降压药物包括利尿剂、钙离子拮抗剂、血管紧张素转化酶抑制剂、血管紧张素受体拮抗剂都是治疗盐敏感性高血压的适用药物,改变我国高盐饮食习惯是盐敏感性高血压一级预防的关键性措施。
Summary： Salt-sensitive hypertension is the result of co-action of genetic mechanism, Ion transport mechanism, endothelium dysfunction mechanism, kidney mechanism, sympathetic nerve system, central nervous system, renin angiotensin aldosterone （ RAA）, endocrine system,insulin resistance mechanism, etc. Apart from salt-restricted treatment, there are other therapies for salt-sensitive hypertension including supply of kalium ion and calcium ion, anti-hypertension medications, immunothera- py, gene therapy, etc. Anti-hypertension medications, including diuretic, calcium antagonist, angiotensin converting enzyme inhibitor and angiotensin receptors antagonist,are suitable drugs in treatment of salt-sensitivive hypertension. Changing do- mestic high-salt-intake custom may be a critical measure for prevention of salt-sensitive hypertension.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2012年第1期41-44,共4页
Chinese Journal of Practical Internal Medicine
关键词
钠
盐敏感性高血压
限盐治疗
sodium
salt-sensitivity hypertension
salt restriction treatment
