摘要
目的:探讨两种类型子宫内膜癌的发病年龄、手术-病理分期、组织学分级、肌层浸润及雌孕激素受体表达的差异,以期增强对非子宫内膜样癌的认识及重视。方法:对455例子宫内膜癌患者的临床病理资料进行回顾性分析。结果:两种类型子宫内膜癌的平均发病年龄、在绝经前后患者中的构成比、组织学分级、手术-病理分期、肌层浸润深度及雌、孕激素受体表达及淋巴结转移情况有统计学差异。结论:非子宫内膜样癌与子宫内膜样腺癌相比,患者发病年龄较大;在已绝经患者中所占比例远高于子宫内膜样腺癌;Ⅲ/Ⅳ期、中、低分化、雌孕激素受体阴性的比例明显高于内膜样腺癌,更易发生深肌层浸润和淋巴结转移。
Objective：To explore the differences of onset age,surgical-pathological stages,histological grades,myometrial invasion,estrogen receptor expression,and progestogen receptor expression between two types of endometrial cancer,in order to enhance the cognition and attention to non-endometrioid adenocarcinoma. Methods：The clinicopathological data of 455 cases with endometrial cancer were analyzed retrospectively. Results：There was significant difference in the average onset age,the proportions of postmenopausal patients and premenopausal patients,histological grades,surgical-pathological stages,the depth of myometrial invasion,estrogen receptor expression,progestogen receptor expression,and lymph node metastasis between the patients with two types of endometrial cancer. Conclusion：Compared with the patients with endometrioid adenocarcinoma,the onset age of the patients with non-endometrioid adenocarcinoma is older;the proportion of postmenopausal patients among the patients with non-endometrioid adenocarcinoma is significantly higher than that among the patients with endometrioid adenocarcinoma;the proportions of stage Ⅲ/Ⅳ,moderate and poor differentiation,negative estrogen receptor and progestogen receptor among the patients with non-endometrioid adenocarcinoma are significantly higher than those among the patients with endometrioid adenocarcinoma,the patients with non-endometrioid adenocarcinoma are prone to deep myometrial invasion and lymph node metastasis.
出处
《中国妇幼保健》
CAS
北大核心
2012年第3期348-349,共2页
Maternal and Child Health Care of China
基金
吉林省科技发展计划项目〔200705252〕
民人教科学〔2008〕47-2-04
关键词
非子宫内膜样癌
发病年龄
手术-病理分期
组织学分级
淋巴结转移
Non-endometrioid carcinoma
Onset age
Surgical-pathological stage
Histological grade
Lymph node metastasis
