摘要
目的观察改良八白散治疗痤疮后色素沉着的临床疗效。方法对30例面部遗留痤疮后色素沉着受试者采用自身前后、双侧对照的方法进行研究，中药组采用改良中药八白散面膜干预，蜂蜜组采用蜂蜜溶液干预，8周后评价干预疗效。结果中药组总有效率为63．33％，蜂蜜组为26．67％，两组总有效率比较，差异有统计学意义（χ^2=8．15，P〈0．05），且中药组受试者自我疗效评价优于蜂蜜组（χ^2=9．64，P〈0．01）。干预后，两组分别检测正常皮肤点与色素沉着点的黑色素值[中药组分别为（156．18±30．68）、（186．44±41．98），蜂蜜组分别为（158．95±26．64）、（182．25±44．03）]较同组干预前[中药组分别为（180．90±33．09）、（202．37±41．14），蜂蜜组分别为（179.92±32．51）、（205．37±43．31）]明显下降泸〈0．01）：经皮水分丢失值[分别为（13．97±4．78）g／m2h、（13．57±3．68）g／m2h]均较干预前[分别为（9．64±3．01）g／m2h、（10．55±3．39）g／m2h]升高（P〈0．01）；中药组干预后角质层含水量（33．72±9．89）％较干预前（35．26±11．41）％无明显变化（P〉0．05），蜂蜜组（32．05±10．34）％则较干预前（37．21±12．24）％降低（P〈0．05）。中药组干预后皮肤弹性Uv／Ue值降低（0．63±0．05），蜂蜜组（0．64±0．05）无明显变化。结论改良八白散面膜具有美白润肤，加速炎症后色素沉着的消退的功效，且可维持角质层含水量，增加皮肤弹性。
Objective To observe the clinical effect of treating pigmentation after acne with Babai dection mask. Methods Bilateral contrasts was adopted. 30 patients who had pigmentation after aches were randomly recruited into a treatment group and a control group. The treatment group was applied with improved Babai dection mask, while the control group was addminated with honey mask. After 8 weeks of treatment, the therapeutic effects were evaluated. Results The total effective rate of the treatment group was 63.33%, while the control group was 26.67%, showing significant difference （P=0.004）. The subjective satisfaction rate of the treatment group was higher than the control group （P=0.002）. The melanin value of normal skin and pigmentation after the treatment [the treatment group： （156.18±30.68）, （186.44±41.98）; the control group： （158.95±26.64）, （182.25 ±44.03） ] was dramatically reduced than before the treatment [the treatment group： （180.90±33.09）, （202.37±41.14） ; the control group： （179.92±32.51）, （205.37±43.31） ] （P〈0.01）. TEWL value of both groups [（13.97±4.78）g/m2h, （13.57±3.68）g/m2h] were higher than those before treatment[ （9.64±3.01） g/m2h, （10.55±3.39） g/m2h] （P〈0.01）. The treatment group（33.72±9.89） % had no change in water capacity than before （35.26±11.41） （P〉 0.05）, while the control group decreased [after the treatment： （32.05 ± 10.34）%, before the treatment （37.21 ±12.24）%]. Uv / Ue value of skin elasticity decreased in the treatment group （0.63±0.05） while no change in the control group （0.64 ±0.05）. Conclusion Improved Babai dection mask had obvious effects in whitening, accelerating regression of post-inflammatory pigmentation, maintaining the water capacity, and increasing skin elasticity.
出处
《国际中医中药杂志》
2012年第1期11-14,共4页
International Journal of Traditional Chinese Medicine
关键词
八白散
面膜
痤疮
色素沉着
Babaidection
Mask： Acne： Pigmentation
