摘要
目的探讨药物合并认知行为治疗对抑郁症患者的疗效及生活质量的影响。方法将72例抑郁症患者随机分为药物合并认知行为治疗组与药物治疗组,治疗观察8周。于治疗前及治疗2、4、8周末采用汉密尔顿抑郁量表(HAM D-24)、临床疗效总评量表(CG I)与副反应量表(TESS)分别评定疗效与不良反应。于治疗前及治疗8周末采用生活质量综合评定问卷(GQOL-74)评定患者生活质量。结果①治疗8周末两组HAM D评分有显著性差异(t=5.12,P<0.01);②两组G I评分治疗6、8周末组间比较有显著性差异(t=2.22,2.65;P<0.05),E I评分治疗8周末组间比较有显著性差异(t=1.95,P<0.05);③研究组治疗8周末除物质生活维度外,其他3个维度评分与对照组比较均有显著性差异(t=2.24,3.34,2.46;P<0.05)。结论药物合并认知行为治疗可提高抑郁症的治疗效果和生活质量。
Objective To explore the effect of medication combined with Cognitive Behavior Therapy（CBT）on the efficacy and quality of life of patients with depression. Methods A total of 72 cases with depression were randomly divided into medication combined with CBT group （n = 36） and medication group （n= 36） for an 8-week observation. Hamilton Depression Rating Scale （HAMD-24）, Clinical Global Impression （CGI） and Treatment Emergent Symptom Scale （TESS） were respectively used to assess the efficacy and side effects before treatment and after 2,4,8 weeks＇ treatment. General quality of life inventory （GQOLI-74） was used to analyze quality of life of these patients at baseline and the end of 8 week. Results ①After 8 weeks＇ treatment,the scores of HAMD between two groups were significantly different （t= 5.12 ,P〈0. 01） ;@There were significant differences in GI score between two groups at 6,8 weekend （t= 2.22,2.65 ;P〈0.05）, and there was significant difference in EI score between two groups at 8 weekend （t = 1.95,P〈0.05） ③After 8 weeks treatment, the scores of the other three dimensions except the material life dimension in research group were significantly higher than those in control group （t= 2. 24,3.34,2.46 （P〈0. 05）. Concl usion Medication combined with CBT can improve the efficacy and quality of life of patients with depression.
出处
《中国健康心理学杂志》
2011年第12期1411-1413,共3页
China Journal of Health Psychology
关键词
精神卫生
认知行为治疗
抑郁症
疗效
生活质量
Mental health
Cognitive behavioral therapy
Depression Efficacy
Quality of life
