摘要
目的了解成人哮喘及慢性咳嗽患者过敏原分布情况。方法选取112例患者(包括46例哮喘患者及66例慢性咳嗽患者)及23名正常对照者过敏原皮肤点刺试验(SPT)结果分为哮喘组、慢性咳嗽组及正常对照组进行分析。结果哮喘组中,最常见的变应原依次为粉尘螨、屋尘螨、热带螨、狗毛、猫毛、德国小蠊,其中粉尘螨、屋尘螨的阳性率均在60%以上;慢性咳嗽组中,最常见的变应原依次为屋尘螨、粉尘螨、热带螨、猫毛、德国小蠊、美洲大蠊等;哮喘组SPT阳性率高于慢性咳嗽组,慢性咳嗽组SPT阳性率高于正常对照组,差异均具有统计学意义。典型哮喘与咳嗽变异性哮喘SPT阳性率无明显差别。结论引起哮喘与慢性咳嗽的主要变应原因素为屋尘螨、粉尘螨、热带螨,SPT在变应性疾病的变应原因素诊断中具有一定意义。
Objective To explore the distribution of allergens inducing adult asthma and chronic cough. Methods 135 subjects were divided into three groups： asthma group, chronic chough group and control group. All subjects were carried on skin prick test to make statistical analysis. Results The most frequent allergens inducing asthma were dermatophagoides farinae, dermatophagoides pteronyssinus, blomia tropiealis, dog hair, eat hair, hlaterlia Germanica etc. Among them, the positive possibility of dermatophagoides farinae and dermatophagoides pteronyssinus were both more than 60%. The most frequent allergens inducing chronic cough were dermatophagoides pteronyssinus, dermatophagoides farinae, blomia tropicalis, cat hair, blaterlia Germanica, American cockroach etc. There was no significant difference on SPT positive rate between typical asthma subgroup and chronic cough subgroup. Conclusions The allergens resulting in asthma and chronic cough were mainly dermatophagoides pteronyssinus, dermatophagoides farinae and blomia tropicalis. Skin prick test was useful for diagnosing allergens in allergic diseases.
出处
《中华哮喘杂志（电子版）》
CAS
2011年第6期11-13,共3页
Chinese Journal of Asthma(Electronic Version)
