摘要
目的 :探讨声带粘膜白斑的分型及其与癌变的关系。方法 :32例 (38侧 )中 ,14例行喉裂开声带粘膜剥皮术 ,其中 2例在显微镜下用下唇粘膜修补创面 ;18例在显微支撑喉镜下行声带粘膜剥皮术。结果 :全组病例随访 2～ 7年。单纯白斑 18例 ,无一例癌变 ;白斑伴轻度不典型增生 6例 ,有 2例发生癌变 (33% ) ;白斑伴中度和重度不典型增生各 4例 ,各有 3例发生癌变 (75 % )。各种不典型增生的癌变率差异无显著性 (P >0 .0 5 )。支撑喉镜下与喉裂开声带粘膜剥皮术 ,均有癌变发生 ,二者差异无显著性。结论 :单纯白斑可以治愈。若同时伴有任何不典型增生病变都要引起高度重视 ,密切随访。两种术式的选择对疗效无影响。
Objective:To investigate the types and curative effects of the leukoplakia of the vocal cord. Method:From 1990 to 1996,32 patients (38 sides) with leukoplakia of vocal cord were operated in our hospital,postoperative follow up ranged from 2 to 7 years. Result:There were eighteen cases of simple leukoplakia and fourteen cases of leukoplakia with mild, moderate and severe atypical hyperplasia in this study. None of simple leukoplakia had malignant change. But there were 33%、75% and 75% of cases had malignant change in the leukoplakia with mild、moderate and severe atypical hyperplasia respectively. To surgical methods,there was no significant difference. in the rate of malignant change either by the microlaryngoscopy or thyrotomy.Conclusion:Simple leukoplakia can be cured. More attention should be paid to the leukoplakia with any types of atypical hyperplasia during clinical management. The postoperative results were not depend on the surgical methods.
出处
《临床耳鼻咽喉科杂志》
CSCD
2000年第1期22-23,共2页
Journal of Clinical Otorhinolaryngology
关键词
声带
粘膜白斑
癌前状态
癌变
Vocal cord Leukoplakia Precancerous conditions
