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口服索他洛尔对甲状腺机能亢进性心房颤动的疗效 被引量:3

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摘要 目的:观察索他洛尔口服治疗甲状腺机体亢进(甲亢)性心房颤动(Af)的治疗效果和安全性,为临床治疗方案的选择提供参考。方法:选取收治的甲状腺机能亢进性心房颤动患者84例,给予口服甲巯咪唑30 mg/d进行抗甲状腺治疗;同时给予口服索他洛尔160 mg/d。1个月为1个疗程,连续治疗3个疗程。观察患者的临床疗效,并比较治疗前后患者T3、T4水平,心率(HR)的变化。结果:治疗3个月后显效20例,有效36例,无效28例,总有效率为66.67%。治疗后患者T3、T4、心率与治疗前比较均有明显降低,差异有统计学意义(P<0.05)。患者出现上腹部不适1例,头晕乏力2例,经减量治疗后好转。结论:采用口服索他洛尔治疗甲状腺机能亢进性心房颤动,可以取得较好的临床疗效,且不良反应小,值得临床推广。
作者 赵凤彦
出处 《吉林医学》 CAS 2011年第36期7723-7723,共1页 Jilin Medical Journal
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  • 1毛文文.甲状腺功能亢进性心脏病的预防和治疗[J].医学综述,2004,10(12):729-731. 被引量:7
  • 2刘灵芝,刘恒亮,武恩平.甲状腺功能亢进性心脏病32例临床分析[J].河南职工医学院学报,2006,18(2):111-113. 被引量:2
  • 3唐元升,朱兴雷.心房颤动治疗的新进展[J].中国实用内科杂志,1997,17(2):118-119. 被引量:8
  • 4Klein I,Ojamaa K. Thyroid hormone and the cardiovascular system [J].New England Jownal of Medicine,2001,344:501 被引量:1
  • 5Shimoni Y, Banno H. Thyroxine effects on tenmperature dependence of ionic currents in single rabbit cardiac myocytes[ J]. Am J Physiol, 1993,265 :H1 875 被引量:1
  • 6Sakaguchi Y, Cui G,Sen L. Acute effects of thyroid hormone on inward rectifier potassium channel currents in guinea pig ventricular myocytes[J]. Endocrinology, 1996,137 ( 11 ) :4 744 被引量:1
  • 7Chen YC,Chen SA,Chen YJ,et al. Effects of thyroid hormone on the arrhythmogenic activity of pulmonary vein cardiomyocytes[J]. J Am Coll Cardiol,2005,39(2) :366 被引量:1
  • 8Chen YJ, Chen SA, Chen YC ,et al. Electrophysiology of single cardiomyocytes isolated from rabbit pulmonary veins:implication in initiation of focal atrial fibrillation [J]. Basic Res cardiol, 2002,97 (1):26 被引量:1
  • 9Kobori H, Ichihara A, Miyashita Y, et al. Local renin-angiotensin system contributes to hyperthyroidism-induced cardiac hypertrophy[J]. J Endocrinol,1999,160( 1 ) :43 被引量:1
  • 10Kobori H, Hayashi M, Saruta T. Thyroid hormone stimulates renin gene expression through the thyroid hormone response element [ J ]. Hypertension ,2001,37 ( 1 ) :99 被引量:1

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  • 1王娟娟,高建国.48例甲亢性心脏病疗效分析[C].第七次全国地方病学术会议论文集,2011:163. 被引量:1
  • 2Karras S,Tzotzas T,Kaltsas T,et al. Pharmacological treatment of hyper-thyroidism during lactation : review of the literature and novel data [J].Pediatr Endocrinol Rev,2010,8( 1) :25-33. 被引量:1
  • 3Ghandour A, Heust C. Hyperthyroidism : a stepwise approach to man-agement [J]. J Fam Pract,2011,60(7);388-395. 被引量:1
  • 4Mansourian AR. A review of literature on the adverse effects of hy-perthyroidism on the heart functional behavior [J]. Pak J Biol Sci,2012,15(4):164-176. 被引量:1
  • 5Brandt F,Green A,Hegediis L,et al. A critical review and meta-anal-ysis of the association between overt hyperthyroidism and mortality [J].Eur J Endocrinol,2011,165(4) :491-497. 被引量:1
  • 6Traube E, Coplan NL. Embolic risk in atrial fibrillation that arises fromhyperthyroidism : review of the medical literature [J]. Tex Heart Inst J,2011,38(3):225^228. 被引量:1
  • 7Me Dermott MT. Hyperthyroidism [J]. Ann Intern Med,2012,157(1):1-16. 被引量:1
  • 8Gurgul E,Sowinski J. Primary hyperthyroidism-diagnosis and treatment.Indications and contraindications for radioiodine therapy [J]. Nucl MedRev Cent East Eur,2011,14(1) :29-32. 被引量:1
  • 9Bal C,Chawla M. Hyperthyroidism and jaundice [J]. Indian J Nucl Med,2010,25(4):131-134. 被引量:1
  • 10Loomba- Albrecht LA,Bremer AA,Styne DM,et al. High frequencyof cardiac and behavioral complaints as presenting symptoms of hy-perthyroidism in children [J]. J Pediatr Endocrinol Metab,2011,24(3-4):209-213. 被引量:1

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