摘要
通过剖析临床药师对1例地高辛中毒的老年扩张型心肌病患者的药学监护服务,探讨如何选择适宜的药学监护切入点,对可能发生的地高辛药物中毒进行药学监护。结合患者个体特点,可以从地高辛血药浓度监测、有无心脏基础疾病及其他影响地高辛敏感性的全身因素或疾患、电解质水平、药物相互作用等方面开展药学监护。改变地高辛敏感性导致患者中毒的危险因素有很多,主要与地高辛的血药浓度、用法用量、患者的基础疾病、电解质水平、肝肾功能、联合用药种类等相关,临床药师可充分发挥药学专业特色,将相关疾病的临床知识与地高辛的作用特点有效结合,对使用地高辛的患者进行有益的药学监护,以避免或减少洋地黄中毒。
One case of pharmaceutical care on an elderly dilated cardiomyopathy patient with digoxin toxicity was analyzed to discuss how to choose the appropriate entry points for monitoring the potential digoxin toxicity.The clinical pharmacists should carry out the pharmaceutical care by considering the following factors as breakthrough points,including individual patient characteristics,monitoring of serum concentration of digoxin,with or without heart disease and other systemic diseases,electrolyte levels,drug interactions and other factors.There were various risk factors associated with poisoning induced by digoxin,such as serum concentration of digoxin,usage and dosage of digoxin,the patient＇s existing physical illness,level of electrolyte,liver and renal function and combination medication.Clinical pharmacist should make good use of pharmaceutical knowledge,and effectively combine the clinical knowledge with characteristics of digoxin,and provide helpful pharmaceutical care on patients using digoxin in order to avoid or reduce the occurrence of poisoning induced by digoxin.
出处
《中国药物应用与监测》
CAS
2011年第6期353-355,共3页
Chinese Journal of Drug Application and Monitoring
关键词
临床药师
药学监护
地高辛
中毒
Clinical pharmacist
Pharmaceutical care
Digoxin
Poisoning
