摘要
目的:探讨输卵管妊娠患者血β-HCG(人绒毛膜促性腺激素)值与滋养细胞增殖活性、滋养细胞对输卵管管壁浸润深度的相关性。方法:在我院行手术治疗的输卵管妊娠患者38例,所有患者于术前2 h内抽取静脉血采用放射免疫法检测血β-HCG值水平;并取术中切除输卵管组织标本进行HE染色,光镜观察。结果:根据病理所见将滋养细胞浸润深度分成三组:Ⅰ组为滋养细胞浸润输卵管黏膜层,Ⅱ组为滋养细胞浸润至肌层,Ⅲ组为滋养细胞浸润至浆膜层(穿透肌层),其中Ⅰ组患者的血β-HCG水平为(1 416.64±659.94)U/L;Ⅱ组为(3 380.33±1 392.36)U/L;Ⅲ组为(6 999.33±2 949.90)U/L。三组比较差异有统计学意义(F=9.914,P<0.05)。结论:输卵管妊娠患者血清β-HCG水平可以作为判断滋养细胞浸润程度的一项指标,值得在临床上推广应用。
Objective：To discuss correlation between serum β-HCG levels and trophoblast cells invasion depth in patients with tubal pregnancy.Methods：38 patients with tubal pregnancy operated in our hospital were selected.Serum β-HCG level of all patients was detected by radioimmunoassay 2 hours before surgery;and the removal tissue specimens of fallopian tube were stained with HE,and they were observed under light microscope.Results：According to the trophoblast invasion depth,the patients were divided into three groups：group Ⅰ（invasive depth to mucosa layer of trophoblastic cells）;group Ⅱ（invasive depth to muscle layer of trophoblastic cells）;group Ⅲ [invasive depth to serosa layer（across muscle layer） of trophoblastic cells].In the group Ⅰ,serum β-HCG level was（1 416.64±659.94） U/L;it was（3 380.33±1 392.36）U/L in group Ⅱ.In the group Ⅲ,serum β-HCG level was（6 999.33±2 949.90） U/L.There were significantly differences among the three groups（F=9.914,P〈0.05）.Conclusion：Serum β-HCG level can detect invasive depth of trophoblastic cells in patients with tubal pregnancy,and it is worth to promote.
出处
《中国医药导报》
CAS
2011年第36期57-58,61,共3页
China Medical Herald
