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兰迪治疗高血压的临床疗效初步观察

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摘要 目的:观察苯磺酸氨氯地平片(兰迪)治疗高血压的降压作用、对心率的影响及安全性。方法:选择原发性高血压患者28例,采取医院内固定医生测量血压,14例同时行24h动态血压监测;予以口服兰迪(2.5~10.0)mg/d,疗程8周。结果:收缩压、舒张压、心率均有明显下降,平均降幅分别为30.7mmHg(1mmHg=0.133kPa)、21.7mmHg、12.8次/min,服药8周后与服药前相比,差异均有统计学意义(P<0.05);28例高血压患者中,显效14例(50.0%),有效12例(42.9%),无效2例(7.1%),兰迪降血压的总有效率达92.9%。治疗4周后,收缩压为(121±11)mmHg,舒张压为(78±6)mmHg,白昼及夜间血压大多控制在130/90mmHg以下,毒副反应可耐受。结论:兰迪是一种安全有效且服用方便的药物,每天服药1次能有效控制24h血压及清晨高峰期血压,是轻、中度高血压患者特别合并缺血性心脏病、心绞痛患者的理想降压药物。
出处 《医学理论与实践》 2011年第24期2949-2950,共2页 The Journal of Medical Theory and Practice
关键词 兰迪 高血压
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