摘要
目的:评价加替沙星、哌拉西林/他唑巴坦和硫酸依替米星这三种抗菌药物治疗尿路感染的疗效和安全性。方法:将120例尿路感染患者分成三组,A组给予加替沙星治疗(40例),B组给予哌拉西林/他唑巴坦治疗(40例),C组给予硫酸依替米星治疗(40例),进行疗效和安全性分析。结果:A、B、C三组治疗尿路感染的临床有效率分别为85%、87.5%和95%;细菌清除率分别为84.2%、88.9%和94.6%;这两项指标中,A和B两组无显著差异(P>0.05),它们与C组差异显著(P<0.05)。三组均未发生严重不良反应,不良反应发生率分别为5%、5%和2.5%。结论:三种抗菌药物治疗尿路感染的效果都很明显,安全性好。其中,硫酸依替米星的治疗效果更显著一些。
Objective： To evaluate the efficacy and safety of three kinds of antibiotics in the treatment of urethral infection. Methods：The patients were divided into three groups. Groups A（40 cases）, B（40 cases）and C（40 cases）were given gatifloxacin, piperacillin/tazobactam and etimicin sulfate, respectively. Results：The clinical effective rates for groups A, B and C were 85%, 87. 5% and 95%, respectively, while the bacterial eliminating rates were 84. 2%, 88. 9% and 94. 6 %, respectively. In these two dectections, the differences were not significant between groups A and B（P〉0. 05） ; however, between groups A and C, B and C, the differences were significant（P〈0. 05）. The drug related adverse events occurred at the rates of 5%, 5% and 7. 5%, respectively, for groups A, B and C, and no severe adverse reaction was observed. Conclusion： All of the three kinds of antibiotics were obviously efficacious and safety in the treatment of urethral infection. Moreover, etimicin sulfate was better than the other two antibiotics.
出处
《医学理论与实践》
2011年第24期2917-2919,共3页
The Journal of Medical Theory and Practice
