摘要
目的探讨慢性肾脏疾病患者的医院感染特点及相关危险因素。方法回顾性分析1079例患者的临床资料和医院感染情况,并填入自制表格,内容包括性别、年龄、住院时间、患者的感染率、感染部位、基础疾病、病原菌等,并采用流行病学方法进行统计分析。结果发生医院感染261例,感染率为24.2%,感染部位以泌尿道为主,占46.4%,原发病中狼疮性肾炎感染率最高,为34.1%;住院时间>30d,医院感染率高达44.7%;共培养、分离出病原菌130株,检出阳性率为49.8%,以革兰阳性菌为主,占66.1%,其次为革兰阴性杆菌占23.1%,真菌占10.8%。结论慢性肾脏疾病患者医院感染与年龄、原发病、肾功能、住院时间等有关,早期预防和治疗医院感染,对于改善肾脏病的预后有良好效果。
OBJECTIVE To investigate the characteristics of nosocomial infection in patients with chronic kidney disease and analyze related risk factors. METHODS Retrospective analysis of medical records and nosocomial infection situation of 1079 patients was conducted, and self-made form was filled, including gender, age, length of stay imhospital, the patient＇s infection rate, the site of infection, underlying diseases, pathogens, etc, and statistics and analysis with epidemiological methodology were carried out. RESULTS The infection rate was 24.2%. The most common infection site was urinary tract, accounting for 46. 4%. Among primary diseases, infection rate of lupus nephritis was the highest, accounting for 34.1%. Longer stay in hospital led to higher rate of infection. Among patients whose duration of hospitalization was more than 30 days, nosocomial infection rate was as high as 44.7 ~. They cultured and isolated 130 strains of bacteria. The positive rate was 49.8 ~. The most common bacteria were Gram-positive bacteria, accounting for 66. 2%, followed by Gram-negative bacteria, accounting for 23.1%, and fungi accounting for 10. 8%. CONCLUSION In patients with chronic kidney disease, nosocomial infection is related to age, primary disease, renal function, length of stay in hospital and so on. Early prevention and treatment of nosocomial infection have good effect in improving prognosis of kidney disease.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第24期5209-5210,共2页
Chinese Journal of Nosocomiology
关键词
慢性.肾脏疾病
医院感染
危险因素
Chronic kidney disease
Nosocomial infection
Risk factors
