摘要
目的观察单纯慢性丙型肝炎与合并脂肪肝的丙肝患者之间病毒载量、瘦素、胰岛素抵抗的差异。方法通过B超筛选慢性丙肝合并脂肪肝患者37例,并与非脂肪变丙肝患者34例比较,观察两组患者病毒载量、肝功能、瘦素、胰岛素抵抗指数差异。结果合并脂肪变的慢性丙型肝炎患者HCV-RNA载量较非脂肪变组明显升高,瘦素水平及胰岛素抵抗较高,HCV-RNA载量与瘦素水平及胰岛素抵抗呈正相关关系,与ALT水平无相关性。结论合并脂肪变的慢性丙型肝炎患者病毒载量与瘦素水平升高及胰岛素抵抗相关。
Objective To observe the simple merger of chronic hepatitis C and fatty liver of hepatitis C viral load between patients,leptin,insulin resistance.Methods The viral load,liver function,leptin,insulin resistance index of 37 chronic hepatitis C patients with fatty liver（fatty group） and 34 cases without fatty liver（non-fatty group） were analyzed.Results The hepatitis C HCV-RNA load,leptin and insulin resistance of fatty group was higher than that of non-fatty group.HCV-RNA load and leptin levels and insulin resistance were positively correlated.Conclusion The viral load of combined steatosis in patients with chronic hepatitis C is related to leptin levels and insulin resistance.
出处
《西部医学》
2011年第12期2326-2327,共2页
Medical Journal of West China
关键词
慢性丙型肝炎
脂肪肝
抗病毒
疗效
Chronic hepatitis C
Fatty liver
Anti-virus
Effect
