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胎儿染色体病的超声筛查分析

Ultrasound Screening for Fetal Chromosomal Diseases
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摘要 目的探求超声在孕中期筛查胎儿染色体病的临床效果和可靠性。方法对2008年1月~2010年12月于宁夏医科大学附属医院接受产前筛查的孕18~24周的孕妇应用超声指标进行孕中期筛查,发现胎儿结构畸形则建议其行产前诊断,对发现2项以上软指标异常的孕妇也建议进行产前诊断。结果接受筛查的11065例孕妇中,异常206例,检出率为1.86%,其中187例接受产前诊断,发现染色体病者16例,继续妊娠至分娩者染色体异常1例,共17例,异常率为9.09%。结论超声检查可有效提高胎儿染色体异常的检出率,减少染色体病胎儿出生,避免不必要的侵入性检查。 Objective To estimate the clinical value and reliability of ultrasound screening for fetal chromosomal diseases in the second trimester. Methods The women at about 18-24 weeks gestation who were willing to accept ultrasound screening were detected in the second trimester. Pregnent women who found foetal deformities or two index were abnormal should auept prenatal diagnosis. Results All of 11 065 pregnant women were screened, and 206 of them were abnormalby ultrasound examination, detection rate was 1.86%, 187 women accept prenatal diagnosis, 16 fetuses' chromosomes were abnormal. One baby was found to be abnormal after birth. So the rate of chromosomal abnormalities was 9.09%. Conclusion Ultrasound screening could increase detection rate of fetal chromosomal abnormality, reduce congenital abnormal babies and avoid excessive invasive examination effectively.
出处 《中国现代医生》 2011年第35期128-129,共2页 China Modern Doctor
关键词 胎儿 染色体病 超声筛查 Fetus Chromosomal disease Ultrasound screening
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参考文献8

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